Results 111 to 120 of about 2,686,988 (365)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Investigation of the thermal stability of Mg/Co periodic multilayers for EUV applications [PDF]
We present the results of the characterization of Mg/Co periodic multilayers and their thermal stability for the EUV range. The annealing study is performed up to a temperature of 400\degree C. Images obtained by scanning transmission electron microscopy
A. Giglia +43 more
core +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The acceleration of materials discovery has gained paramount importance due to its potential to overcome constraints in emerging technologies. Extensive exploration has been undertaken into three pivotal approaches: combinatorial synthesis, high ...
Khurram Shahzad +2 more
semanticscholar +1 more source
Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications [PDF]
This work reports on the development and characterization of novel meltable polymers and composites based on casein and soybean proteins. The effects of inert (Al(2)O(3)) and bioactive (tricalcium phosphate) ceramic reinforcements over the mechanical ...
Adriano +23 more
core +3 more sources
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Hierarchically porous polymers can unite macro-scale architected voids with micro-scale pores, enabling unique combinations of low density, high surface area, and controlled transport properties that are difficult to achieve with traditional methods ...
Savvas Koltsakidis, Dimitrios Tzetzis
doaj +1 more source
This research attempts to propose the fabrication and characterization of highly amorphous zinc silicate glasses derived from zinc oxide (ZnO) and white rice husk ash (WRHA).
Siti Aisyah Abdul Wahab +8 more
doaj +1 more source
Characterizing Semantic Ambiguity of the Materials Science Ontologies
Growth in computational materials science and initiatives such as the Materials Genome Initiative (MGI) and the European Materials Modelling Council (EMMC) has motivated the development and application of ontologies. A key factor has been increased adoption of the FAIR principles, making research data findable, accessible, interoperable, and reusable ...
McClellan, Scott +4 more
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

