Results 121 to 130 of about 1,911,436 (333)

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Innovative Design of a 3D Printed Esophageal Stent Inspired by Nature: Mitigating Migration Challenges in Palliative Esophageal Cancer Therapy

Biomimetics
Esophageal cancer is a complex and challenging tumor to treat, with esophageal stenting being used as a palliative measure to improve the quality of life of patients.
Thomas Profitiliotis, Savvas Koltsakidis, Konstantinos Tsongas, Dimitrios Tzetzis   +3 more
doaj   +1 more source

Binney/Dowrick: The Theory of Critical Phenomena/Brown: Quantum Field Theory/Lifshin: Materials Science and Technology: Vol. 2A, Characterization of Materials, Part I/Cowley: Electron Diffraction Techniques, Volume 1/Bellac: Quantum and Statistical Field Theory/Hehl, Winkelmann u Meyer: Computer‐Algebra/Enderlein u Schenk: Grundlagen der Halbleiter‐physik/Lossau: Wenn Computer denken lernen: Neuronale Netzwerke/Galison u Hevley: Big Science: The Growth of Large‐Scale Research [PDF]

, 1993
Reimer Kühn, H. Reeh, K. Urban, E. Bauer, Hartmann Römer, H. Perlt, H. Jorke, F. J. van den Brand, M. Herdy, D. Hoffmann   +9 more
openalex   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Applications of synchrotron radiation to materials science: Diffraction imaging (topography) and microradiography [PDF]

Synchrotron radiation sources are now available throughout the world. The use of hard X-ray radiation from these sources for materials science is described with emphasis on diffraction imaging for material characterization.
Kuriyama, Masao
core   +1 more source

Dendrimer-induced synthesis of subnano materials and their characterization: establishing atom hybrid science

Bulletin of the Chemical Society of Japan
Abstract The precise molecular design of functional dendritic polymers enables the accumulation of multiple metals within a molecular cage. We have established a synthesizing methodology of metallodendrimers where the number of constituent atoms, the choice of elements, and the composition ratio were precisely controlled through an ...
Akiyoshi Kuzume, Kimihisa Yamamoto
openalex   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Tracking materials science data lineage to manage millions of materials experiments and analyses [PDF]

, 2019
In an era of rapid advancement of algorithms that extract knowledge from data, data and metadata management are increasingly critical to research success.
Gregoire, John M., Guevarra, Dan, Soedarmadji, Edwin, Stein, Helge S., Suram, Santosh K.   +4 more
core  

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

MoS2-Based Photodetectors Powered by Asymmetric Contact Structure with Large Work Function Difference

Nano-Micro Letters, 2019
Self-powered devices are widely used in the detection and sensing fields. Asymmetric metal contacts provide an effective way to obtain self-powered devices.
Zhe Kang, Yongfa Cheng, Zhi Zheng, Feng Cheng, Ziyu Chen, Luying Li, Xinyu Tan, Lun Xiong, Tianyou Zhai, Yihua Gao   +9 more
doaj   +1 more source