Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Development of 4D-Printed Arterial Stents Utilizing Bioinspired Architected Auxetic Materials
BiomimeticsThe convergence of 3D printing and auxetic materials is paving the way for a new era of adaptive structures. Auxetic materials, known for their unique mechanical properties, such as a negative Poisson’s ratio, can be integrated into 3D-printed objects to
Nikolaos Kladovasilakis +5 more
doaj +1 more source
Polymer processing and characterization Advances in materials science, Volume 1 Editors: Sabu Thomas, Deepalakshmi Ponnamma, and Ajesh K. Zachariah [PDF]
, 2012 openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
iScienceSummary: In situ liquid-phase electrochemical transmission electron microscopy (ec-TEM) as a valuable technique has been widely used in studying metal deposition in battery materials.
Xin Wei, Michael Noyong, Ulrich Simon
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Binney/Dowrick: The Theory of Critical Phenomena/Brown: Quantum Field Theory/Lifshin: Materials Science and Technology: Vol. 2A, Characterization of Materials, Part I/Cowley: Electron Diffraction Techniques, Volume 1/Bellac: Quantum and Statistical Field Theory/Hehl, Winkelmann u Meyer: Computer‐Algebra/Enderlein u Schenk: Grundlagen der Halbleiter‐physik/Lossau: Wenn Computer denken lernen: Neuronale Netzwerke/Galison u Hevley: Big Science: The Growth of Large‐Scale Research [PDF]
, 1993 Reimer Kühn +9 more
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