Results 291 to 300 of about 2,686,988 (365)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Gradient-Nested Organic/Inorganic Aerogels Achieve High Mechanical Strength and Feedback-Tunable Microwave Absorption. [PDF]

Research (Wash D C)
Liu X, Si Z, Qian Y, Wu L, Xu X, Wan G, Wang G.   +6 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Application of Membrane Materials in Bioseparation and Downstream Processing. [PDF]

Membranes (Basel)
Zhang W, Kong L.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

High-efficiency broadband active metasurfaces via reversible metal electrodeposition. [PDF]

Light Sci Appl
Li Q, Kulkarni SP, Sui C, Chen TH, Yan G, Wu R, Chen W, Hung PJ, Wu X, Emersic T, Aydin K, Hsu PC.   +11 more
europepmc   +1 more source

From negligible to giant electrocaloric effect of poly(vinylidene fluoride). [PDF]

Nat Commun
Zhang Y, Ye Z, Niu F, Xiong C, Wang W, Fu Y, Zhang S, Wang S, Yang Q, Qin H, Liu S, Wang Q.   +11 more
europepmc   +1 more source

Sustainable Nonenantioselective Production and Stereochemical Characterization of the Lignin-Derived Chiral Building Block 3-Carboxymuconolactone. [PDF]

ChemistryOpen
Suzuki Y, Araki T, Fujita M, Kamimura N, Masai E, Michinobu T, Otsuka Y, Hishiyama S, Nakamura M.   +8 more
europepmc   +1 more source