Results 231 to 240 of about 1,876,346 (290)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Laser-printed document classification using random forest and gray prediction models. [PDF]

iScience
Qu Y, Yu C, Li C, Yang Y.
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

An interpretable alphabet for local protein structure search based on amino acid neighborhoods. [PDF]

Bioinformatics
Zerefa S, Cool J, Singh P, Petti S.
europepmc   +1 more source

Nuances of Gender Identity for a Transgender Patient Receiving Inpatient Treatment for Paranoid Schizophrenia: A Case Study. [PDF]

Case Rep Psychiatry
Suri RK, Heslin KP, Sperry S, Leontieva L.   +3 more
europepmc   +1 more source

How youth think about structural, individual, and random sources of wealth inequality. [PDF]

J Exp Child Psychol
Burkholder AR, Sims RN, Killen M.
europepmc   +1 more source

Efficient algorithms for simulating sequences along a phylogenetic tree. [PDF]

Bioinformatics
Wygoda E, Moshe A, Serok N, Dotan E, Ecker N, Jabareen N, Israeli O, Pe'er I, Pupko T.   +8 more
europepmc   +1 more source

PlaceMyFossils: An Integrative Approach to Analyze and Visualize the Phylogenetic Placement of Fossils Using Backbone Trees. [PDF]

Syst Biol
Catalano SA, Escapa I, Pugh KD, Hammond AS, Goloboff P, Almécija S.   +5 more
europepmc   +1 more source

How many characters are needed to reconstruct a phylogeny?

Capobianco A.
europepmc   +1 more source

Predictors of Professional Responses in Nonprofit Mental Health Forums: Interpretable Machine Learning Analysis.

J Med Internet Res
Geng S, Li Y, Wang J, Chen P, Wu X, Zhang Z.   +5 more
europepmc   +1 more source