Results 231 to 240 of about 87,063 (285)
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Orthopaedic Nursing, 2001
Charcot joint is the painless, degenerative, progressive neuropathic destruction of the bony architecture of one or more joints of the feet. Diabetes mellitus is the most common cause of Charcot joint in North America, although the exact etiology is uncertain. The classic presenting complaint involves unilateral painless swelling of the lower extremity
D S, Houston, J, Curran
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Charcot joint is the painless, degenerative, progressive neuropathic destruction of the bony architecture of one or more joints of the feet. Diabetes mellitus is the most common cause of Charcot joint in North America, although the exact etiology is uncertain. The classic presenting complaint involves unilateral painless swelling of the lower extremity
D S, Houston, J, Curran
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Der Orthopäde, 1999
Charcot foot in its original sense is equivalent to stage 4 of hereditary motor and sensory neuropathy (HMSN) which is known as Charcot-Marie-Tooth disease since 1886. This entity, which can be subdivided into 3 groups including subgroups, predominantly begins during childhood and progresses slowly. The first symptom, often unnoticed by the patient for
H, Zwipp +3 more
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Charcot foot in its original sense is equivalent to stage 4 of hereditary motor and sensory neuropathy (HMSN) which is known as Charcot-Marie-Tooth disease since 1886. This entity, which can be subdivided into 3 groups including subgroups, predominantly begins during childhood and progresses slowly. The first symptom, often unnoticed by the patient for
H, Zwipp +3 more
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HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease
Brain, 2018 Patients with Charcot-Marie-Tooth disease with predominant axonal loss (CMT2) show extensive genetic heterogeneity. Benoy et al. demonstrate a link between CMT2 and histone deacetylase 6 (HDAC6), which controls the acetylation of α-tubulin, and propose ...
Veronick Benoy +2 more
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Nature Communications, 2018 Dominant mutations in glycyl-tRNA synthetase (GlyRS) cause a subtype of Charcot-Marie-Tooth neuropathy (CMT2D). Although previous studies have shown that GlyRS mutants aberrantly interact with Nrp1, giving insight into the disease’s specific effects on ...
Xiaobei Zhao, Xu-Qiao Chen, Na Wei
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British Journal of Hospital Medicine, 2008
A 55-year-old man with insulindependent diabetes mellitus was referred by his GP with a 3-month history of a red, warm, swollen foot that can clinically mimicked cellulitis and had failed to respond to oral antibiotics. Plain radiographs (Figure 1) and magnetic resonance imaging (Figure 2) showed a dislocation of the tarsometatarsal joint with diffuse
Rupen, Dattani +2 more
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A 55-year-old man with insulindependent diabetes mellitus was referred by his GP with a 3-month history of a red, warm, swollen foot that can clinically mimicked cellulitis and had failed to respond to oral antibiotics. Plain radiographs (Figure 1) and magnetic resonance imaging (Figure 2) showed a dislocation of the tarsometatarsal joint with diffuse
Rupen, Dattani +2 more
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Neurosurgery, 1991
Abstract Charcot joints of the spine are well-documented clinical entities most commonly associated with tabes dorsalis. Spinal neuropathic joints, however, may be produced by other disease processes including syringomyelia. In this review, the authors discuss the cause and treatment of spinal Charcot arthropathy with emphasis on ...
M J, Harrison +3 more
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Abstract Charcot joints of the spine are well-documented clinical entities most commonly associated with tabes dorsalis. Spinal neuropathic joints, however, may be produced by other disease processes including syringomyelia. In this review, the authors discuss the cause and treatment of spinal Charcot arthropathy with emphasis on ...
M J, Harrison +3 more
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The Lancet, 2002
The Charcot foot Neuroarthropathy, or Charcot foot, was first described by Jean-Martin Charcot in 1883 in patients with tabes dorsalis, but nowadays it is reported most frequently as a complication of diabetes. Two-thirds of people with Charcot foot have type 2 diabetes. Men and women are equally affected. The disorder affects about 0.2% of people with
Agnès, Hartemann-Heurtier +2 more
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The Charcot foot Neuroarthropathy, or Charcot foot, was first described by Jean-Martin Charcot in 1883 in patients with tabes dorsalis, but nowadays it is reported most frequently as a complication of diabetes. Two-thirds of people with Charcot foot have type 2 diabetes. Men and women are equally affected. The disorder affects about 0.2% of people with
Agnès, Hartemann-Heurtier +2 more
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Neurosurgery, 2003
The Charcot library was officially created at the Salpêtrière Hospital in 1907 after the donation of the private library of Jean-Martin Charcot, which Dr. Charcot had accumulated progressively throughout his professional career. Increased by several other endowments (the most important being the collection of the Resident's Library, begun in 1886) and ...
Jacques H, Philippon +3 more
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The Charcot library was officially created at the Salpêtrière Hospital in 1907 after the donation of the private library of Jean-Martin Charcot, which Dr. Charcot had accumulated progressively throughout his professional career. Increased by several other endowments (the most important being the collection of the Resident's Library, begun in 1886) and ...
Jacques H, Philippon +3 more
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Foot and Ankle Clinics, 2000
Charcot's foot used to be considered an unusual complication of diabetic peripheral neuropathy. With the current appreciation that approximately 25% of adult diabetics have an appreciable peripheral neuropathy, it is understandable that Charcot's neuro-osteoarthropathy has become recognized as a major problem for clinicians caring for diabetics ...
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Charcot's foot used to be considered an unusual complication of diabetic peripheral neuropathy. With the current appreciation that approximately 25% of adult diabetics have an appreciable peripheral neuropathy, it is understandable that Charcot's neuro-osteoarthropathy has become recognized as a major problem for clinicians caring for diabetics ...
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Medical Clinics of North America, 2013
The diabetic Charcot foot is rare, but a life-changing event affecting quality of life, and it risks amputation of the limb. There is no high quality evidence base governing treatment, causing clinicians to rely on low-quality, underpowered studies and expert opinion.
Lee C, Rogers, Robert G, Frykberg
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The diabetic Charcot foot is rare, but a life-changing event affecting quality of life, and it risks amputation of the limb. There is no high quality evidence base governing treatment, causing clinicians to rely on low-quality, underpowered studies and expert opinion.
Lee C, Rogers, Robert G, Frykberg
openaire +2 more sources