Results 51 to 60 of about 78,454 (292)
Arthritis &Rheumatology, EarlyView.Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley +1 more source
Associação na mesma família das doenças de Charcot-Marie-Tooth e de Friedreich
Arquivos de Neuro-Psiquiatria, 1972 Quatro irmãos com moléstias de Charcot-Marie-Tooth são estudados do ponto de vista clínico e genético. São ressaltadas, mediante análise da sintomatologia, as formas de transição no grande grupo de moléstias heredodegenerativas, sendo atribuída ...
Charles Peter Tilbery +3 more
doaj +1 more source
BMJ, 2012 #### Key points A 38 year old man was referred by his general practitioner to our diabetes foot clinic with a swollen red foot (fig 1⇓). He had had type 1 diabetes for 25 years, complicated with retinopathy, peripheral neuropathy, and nephropathy, and was being worked up for dialysis following a failed pancreas-kidney transplant.
Piero, Baglioni +2 more
openaire +2 more sources
Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss [PDF]
, 2005 This review on the role of neurofilaments as surrogate markers for axonal degeneration in neurological diseases provides a brief background to protein synthesis, assembly, function and degeneration.
Petzold, A
core +1 more source
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
Cytoskeleton, EarlyView.ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
Management of hindfoot and ankle in Charcot arthropathy
EFORT Open ReviewsCharcot neuroarthropathy is the most severe complication of the diabetic foot. Its diagnosis is difficult and often overlooked, delaying management, with sometimes disastrous consequences.
Nicolas Cellier
doaj +1 more source
Ancient Schwannoma of the Cauda Equina: our experience and review of the literature [PDF]
, 2016 Ancient schwannomas (AS) are exceedingly rare variant of common schwannomas (CS). Only two cases involving the cauda equina region have been previously reported in literature.
Caruso, Riccardo +5 more
core +4 more sources
Flavour and Fragrance Journal, EarlyView.We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan +9 more
wiley +1 more source
Hemoglobin A1C in Charcot: Can It Predict a BKA?
Foot & Ankle Orthopaedics, 2022 Category: Diabetes; Ankle; Trauma; Other Introduction/Purpose: Charcot Foot is a serious and potentially limb-threatening complication of longstanding diabetes, peripheral neuropathy, and trauma.
Brandon J. Martinazzi BS +5 more
doaj +1 more source
Rehabilitation interventions for foot drop in neuromuscular disease [PDF]
, 2009 "Foot drop" or "Floppy foot drop" is the term commonly used to describe weakness or contracture of the muscles around the ankle joint.
Brumett +33 more
core +1 more source