Results 81 to 90 of about 78,454 (292)
Brain Age Estimation on T2‐FLAIR Scans for Application to Multiple Sclerosis
Human Brain Mapping, Volume 47, Issue 5, 1 April 2026.While the brain‐age paradigm has emerged as a promising biomarker of neurodegeneration in multiple sclerosis (MS), most available brain‐age prediction models are based on 3D‐T1w scans, which are not acquired in routine clinical practice. Leveraging a large multicentre collection of scans from healthy controls, we developed an accurate brain‐age ...
Jordan Colman +46 more
wiley +1 more source
A case presentation of Charcot s joint which is caused by arachnoid cyst
Acta Orthopaedica et Traumatologica Turcica, 2021 Charcot s joint is a destructive arthropathy, which develops in weight bearing joints, due to pain and proprioseptive sensory absence. it is most often seen in the knee. the hip, and ankle. Vertebra is rarely involved. An 18 year-old women treated by the
M. Cevdet Avkan +3 more
doaj +2 more sources
Scientific Reports, 2017 Charcot arthropathy is one of the most serious complications of diabetic foot syndrome that leads to amputation of the affected limb. Since there is no cure for Charcot arthropathy, early diagnosis and implementation preventive care are the best ...
Bożena Bruhn-Olszewska +3 more
doaj +1 more source
OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability. [PDF]
, 2012 BackgroundMitochondrial fusion protein mutations are a cause of inherited neuropathies such as Charcot-Marie-Tooth disease and dominant optic atrophy.
Bers, Donald M +10 more
core +2 more sources
Muscle &Nerve, Volume 73, Issue 4, Page 517-526, April 2026.ABSTRACT CNTNAP1 encodes the Contactin‐Associated Protein 1 (CNTNAP1), also known as Caspr1, which is a transmembrane protein critical for nervous system function. CNTNAP1 is localized to the paranodal regions of all myelinated axons, flanking either side of the node of Ranvier.
Lacey B. Sell +8 more
wiley +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
PLoS ONE, 2020 ObjectiveAggressive antidiabetic therapy and rapid glycemic control are associated with diabetic neuropathy. Here we investigated if this is also the case for Charcot neuroarthropathy.Research design and methodsHbA1c levels and other relevant data were ...
Dured Dardari +10 more
doaj +1 more source
Expanding the Genotype and Phenotype Diversity in a Chinese Cohort With TRPV4‐Related Dysplasia
Clinical Genetics, Volume 109, Issue 4, Page 796-802, April 2026.Exploring the genotype and phenotype diversity in a Chinese cohort with TRPV4‐related dysplasia. ABSTRACT Dominant mutations in the calcium permeable ion channel TRPV4 (transient receptor potential vanilloid 4) typically result in skeletal dysplasia or peripheral neuromuscular disease.
Lina Dong +8 more
wiley +1 more source
Journal of NeuroinflammationNeuroinflammation is a key driver of neurodegenerative disease, however the tools available to model this disease biology at the systems level are lacking.
Kelley C. Larson +7 more
doaj +1 more source
Foot & Ankle Orthopaedics, 2018 Category: Diabetes Introduction/Purpose: Diabetic Charcot neuroarthropathy is characterized by rapid loss of bone with accompanied disruption to the surrounding joints and is often in the absence of trauma or infection. Previous research has demonstrated
Kaitlin Saloky BS +5 more
doaj +1 more source