Results 81 to 90 of about 37,325 (255)
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley +1 more source
Quatro irmãos com moléstias de Charcot-Marie-Tooth são estudados do ponto de vista clínico e genético. São ressaltadas, mediante análise da sintomatologia, as formas de transição no grande grupo de moléstias heredodegenerativas, sendo atribuída ...
Charles Peter Tilbery +3 more
doaj
Background Proinflammatory cytokines are an integral part of the osteolytic activity of Charcot arthropathy but are also central to normal bone healing.
Agnetha Folestad +6 more
doaj +1 more source
Programmed Cell Death in Chronic Rhinosinusitis
ABSTRACT Chronic rhinosinusitis (CRS) is a prevalent upper respiratory condition characterized by a multifaceted etiology involving various cellular and molecular processes. In recent years, researchers have increasingly recognized the significance of different forms of programmed cell death (PCD), such as apoptosis and pyroptosis, in the pathological ...
Xingchen Liu +5 more
wiley +1 more source
ABSTRACT Background Diabetes mellitus (DM) causes a great majority of non‐traumatic major and minor amputations worldwide; up till now, this condition in developing countries, particularly those in sub‐Saharan Africa, including Sudan, is underestimated. Aim To determine the indications and outcomes of toe amputation among T2DM patients.
ELsiddig ELzubair Ali Mohamed +3 more
wiley +1 more source
Leçons de 1875 / Charcot, Jean Martin
Leçons, 250 feuillets (Fonds Charcot : Manuscrits des leçons de J.M.Charcot.
Charcot, Jean Martin
core
Biological Drivers of IMiD‐Induced Peripheral Neuropathy in Multiple Myeloma
ABSTRACT The introduction of immunomodulatory drugs (IMiDs), such as thalidomide, lenalidomide and pomalidomide, have led to significant improvements in multiple myeloma (MM) treatment. Many patients now live 10 years or longer with their disease, making treatment‐related side effects increasingly important.
Sina A. Beer +2 more
wiley +1 more source
Germain L. Jean Charcot. In: La Terre et La Vie, Revue d'Histoire naturelle, tome 7, n°1, 1937. pp. 1-5.
openaire +3 more sources
Current Topics of Progressive Cardiac Conduction Disease
Many genes and the protein cause PCCD. Mutation of NaV1.5 or CX40 cause isolated PCCD, but mutation of lamin A/C, emerin, or desmin lead to cardiomyopathy, and PCCD. Mutation of transcription factor NCX2‐5, and Tbx5 associated with atrial septal defect and abnormal development of conduction system.
Naokata Sumitomo +7 more
wiley +1 more source
This study demonstrates that high radiological severity in patients with CRSwNP is uniquely characterized by a mixed Type 2 and Type 3 epithelial inflammatory signature. These findings suggest that severe disease involves a complex immune endotype, providing new insights into precision therapeutic strategies for refractory CRSwNP.
Guangfu Xu +5 more
wiley +1 more source

