Results 51 to 60 of about 461,709 (265)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Experimental Charge Density Analysis and Electrostatic Properties of Crystalline 1,3-Bis(Dimethylamino)Squaraine and Its Dihydrate from Low Temperature (T = 18 and 20 K) XRD Data

Crystals, 2020
Multipolar refinements of structural models fitting extensive sets of X-ray diffraction (XRD) data from single crystals of 1,3-bis(dimethylamino)squaraine [SQ, C8H12N2O2] and its dihydrate [SQDH, C8H12N2O2·2H2O], collected at very low T (18 ± 1 K for SQ,
Riccardo Destro, Pietro Roversi, Raffaella Soave, Arjan Hovestad, Leonardo Lo Presti   +4 more
doaj   +1 more source

The nature of π-hole interactions between iodide anions and quinoid rings in the crystalline state

IUCrJ, 2023
The investigated co-crystal of 3-chloro-N-methylpyridinium iodide with tetrabromoquinone (3-Cl-N-MePy·I·Br4Q) reveals a π-hole interaction between an iodide anion and a quinoid ring involving an n → π* charge transfer.
Valentina Milašinović, Vedran Vuković, Anna Krawczuk, Krešimir Molčanov, Christoph Hennig, Michael Bodensteiner   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Influence of thunderstorm cloud on the performance of satellite-to-ground quantum link and parameters simulation

Tongxin xuebao, 2017
In order to investigate the effect of thunderstorm cloud on the performance of satellite-to-ground quantum link,according to the extinction cross section and the number concentration distribution function of the charged particle in the thunderstorm cloud,
Min NIE, Li SHI, Guang YANG, Chang-xing PEI   +3 more
doaj  

Understanding cationic polyelectrolyte thermogels with varying charge densities toward biomaterials design

BMEMat
Polyurethane thermogels are attractive materials for biomedical applications due to their reversible temperature‐controlled gelation that allows for in situ gelation at physiological temperatures. However, traditional thermogels are limited by their lack
Belynn Sim, Yi Jing Wong, Hamzah Kamaruddin, Qianyu Lin, Pablo Mota‐Santiago, Nigel Kirby, Alexis Lee, Yihao Leow, Alice Anhan Chen, Rubayn Goh, Xian Jun Loh   +10 more
doaj   +1 more source

About Calculus Through the Transfer Matrix Method of a Beam with Intermediate Support with Applications in Dental Restorations

Mathematics
This work presents an original and very interesting approach to a calculus problem involving beams with intermediate supports through the transfer-matrix method, a very easy method to program to quickly obtain good results. To exemplify the applicability
Otilia Cojocariu-Oltean, Mihai-Sorin Tripa, Iulia Bărăian, Doina-Iulia Rotaru, Mihaela Suciu   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Structure and Capacitance of Electrical Double Layers at the Graphene–Ionic Liquid Interface

Applied Sciences, 2017
Molecular dynamics simulations are carried out to investigate the structure and capacitance of the electrical double layers (EDLs) at the interface of vertically oriented graphene and ionic liquids [EMIM]+/[BF4]−.
Pengfei Lu, Qiaobo Dai, Liangyu Wu, Xiangdong Liu   +3 more
doaj   +1 more source