Results 81 to 90 of about 627,898 (258)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Charge- and Orbital-Order Transitions in the A-Site-Ordered Quadruple Perovskite NdCuMn6O12

open access: yesInorganics
AMn7O12 perovskites (with A = divalent elements) show complex structural and magnetic transitions including incommensurate orbital density waves and coupled/decoupled modulated spin helicity originating from charge-ordered Mn3+/Mn4+ cations with the 3:1 ...
Alexei A. Belik   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Structural order enhances charge carrier transport in self-assembled Au-nanoclusters

open access: yesNature Communications, 2020
The collective properties of atomically precise nanoclusters bear vast potential for electronic materials by design. Here, the authors describe the self-assembly of Au32 nanoclusters into micro-crystals, which improves the electric conductivity and ...
Florian Fetzer   +8 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Palmierite‐Type Oxyhydride Ba3V2H0.5O7.5 With Vanadium Charge Ordering

open access: yesSmall Structures
Hydride ions (H−) are attracting increasing interest as alternative charge carriers to protons in electrochemical devices; however, the development of H–/e– mixed conductors remains challenging.
Hiroshi Yaguchi   +7 more
doaj   +1 more source

Condensation of collective charge ordering in chromium

open access: yesPhysical Review B, 2015
Here we report on the dynamics of the structural order parameter in a chromium film using synchrotron radiation in response to photo-induced ultra-fast excitations. Following transient optical excitations the effective lattice temperature of the film rises close to the Néel temperature and the charge density wave (CDW) amplitude is reduced. Although we
Singer, A   +11 more
openaire   +5 more sources

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