Results 161 to 170 of about 18,047 (254)

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Development and validation of a novel pulse optimization and beam control system for conventional and ultra high dose-per-pulse (FLASH) irradiation. [PDF]

Med Phys
Connell L, Esplen N, Lim R, Baikalov A, Coupey N, Nguyen C, Schüler E.   +6 more
europepmc   +1 more source

On‐Water Surface Synthesis of 2D Conjugated Metal–Organic Framework Films With Controllable Layer Orientation Enabling High‐Performance Chemiresistive Sensing

Advanced Materials, EarlyView.
Layer orientation dictates charge transport in 2D conjugated metal–organic frameworks, yet controllable methods remain scarce. We report surfactant monolayer‐assisted on‐water synthesis of cm2‐scale Ni‐HHTP films with programmable face‐on and edge‐on orientations.
Jianjun Zhang, Víctor García‐López, Yutong Wu, Shuai Fu, Yucong Chen, Arsh S. Hazrah, Petko Petkov, Mike Hambsch, Feng Ni, Alina Müller, Ye Yang, Leif Riemenschneider, Shirong Huang, Albertus Mattheüs Sandee, Yilv Guo, David Silva‐Brea, Jan‐Ole Joswig, Stefan C. B. Mannsfeld, Thomas Heine, Gianaurelio Cuniberti, Mischa Bonn, Zhiyong Wang, Xinliang Feng   +22 more
wiley   +1 more source

Inkjet-Printed Rough Gold Microelectrode Arrays on Flexible Substrates for Neural Recording and Electrical Stimulation. [PDF]

ACS Appl Mater Interfaces
Ziller A, Corna A, Bui MT, Werginz P, Schneider M, Schmid U, Zeck G.   +6 more
europepmc   +1 more source

Intimate Interaction Between Nucleic Acid and Conjugated Polymers in Organic Electrochemical Transistors Enables Ultrasensitive Biomarker Detection

Advanced Materials, EarlyView.
The intimate interaction between negatively charged RNA molecules and conjugated polymers in organic electrochemical transistors (OECTs) in aqueous electrolytes is investigated. It demonstrates that RNA binding reduces the volumetric capacitance of the polymer channel, enabling the development of an ultrasensitive biosensing platform capable of ...
Hong Liu, Naixiang Wang, Anneng Yang, Jiajun Song, Li Li, Iain McCulloch, Helen Ka‐wai Law, Feng Yan   +7 more
wiley   +1 more source

Development of Compact Electronics for QEPAS Sensors. [PDF]

Sensors (Basel)
Zecchino V, Lombardi L, Marzocca C, Patimisco P, Sampaolo A, Spagnolo VL.   +5 more
europepmc   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

A Flexible Triboelectric-Based Sensor for Seismocardiography Monitoring. [PDF]

Biosensors (Basel)
Wang C, He Y, Peng H, Luo H, Wang X.
europepmc   +1 more source

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

Advanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu, Ondřej Adam, Marek Doubrava, Ana M. Beltrán, Ivo Dlouhý, Xin Liu, Baiyan Sui, Aldo R. Boccaccini   +7 more
wiley   +1 more source

Evaluation of an event-driven 3FI ASIC for spectroscopic X-ray detection with synchrotron radiation. [PDF]

J Synchrotron Radiat
Maj P, Deptuch GW, Gorni DS, Pinaroli G, Carini GA, Siddons DP, Tappero R, Mandal S, Pinelli D, Kersten T, St John N, Rumaiz AK, Kuczewski A.   +12 more
europepmc   +1 more source