Results 131 to 140 of about 363,384 (319)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Absence of intrinsic electric conductivity in single dsDNA molecules [PDF]

open access: yes, 2004
Kleine H, Wilke R, Pelargus C, et al. Absence of intrinsic electric conductivity in single dsDNA molecules. Journal of Biotechnology. 2004;112(1-2):91-95.The intrinsic dc conductivity of long, individual lambda phage dsDNA molecules has been investigated
Rott, Karsten   +7 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Repurposing DNA-binding agents as H-bonded organic semiconductors

open access: yesNature Communications, 2019
To unlock the potential of biological semiconductors for printed flexible electronics, experimental evidence that reveals the material’s charge transport mechanism is required.
Fengjiao Zhang   +7 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Space Charge Formation and its Modified Electric Field under Applied Voltage Reversal and Temperature Gradient in XLPE Cable [PDF]

open access: yes, 2008
The results of space charge evolution in cross-linked polyethylene power cables under dc electrical field at a uniform temperature and during external voltage polarity reversal are presented in the paper.
Fu, Mingli   +11 more
core   +1 more source

Inverted device architecture for high efficiency single-layer organic light-emitting diodes with imbalanced charge transport

open access: yesNature Communications
Many wide-gap organic semiconductors exhibit imbalanced electron and hole transport, therefore efficient organic light-emitting diodes require a multilayer architecture of electron- and hole-transport materials to confine charge recombination to the ...
Xiao Tan   +9 more
doaj   +1 more source

Unexpected behaviors in molecular transport through size-controlled nanochannels down to the ultra-nanoscale

open access: yesNature Communications, 2018
Transport through nanochannels is usually dominated by electrostatic interactions and depends on the charge of diffusing molecules. Here the authors show that for channel heights between 2 and 4 nanometers, transport is insensitive to molecule charge.
Giacomo Bruno   +12 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

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