Results 31 to 40 of about 269,147 (313)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Charged-current non-standard neutrino interactions at Daya Bay
The full data set of the Daya Bay reactor neutrino experiment is used to probe the effect of the charged current non-standard interactions (CC-NSI) on neutrino oscillation experiments.
The Daya Bay collaboration +201 more
doaj +1 more source
Charge and current distribution in graphs [PDF]
We consider graphs made of one-dimensional wires connected at vertices, and on which may live a scalar potential. We are interested in a scattering situation where such a network is connected to infinite leads. We study the correlations of the charge in such graphs out of equilibrium, as well as the distribution of the currents in the wires, inside the
Texier, Christophe, Degiovanni, Pascal
openaire +4 more sources
Charge conservation, entropy current and gravitation
We propose a new class of vector fields to construct a conserved charge in a general field theory whose energy–momentum tensor is covariantly conserved. We show that there always exists such a vector field in a given field theory even without global symmetry.
Aoki, Sinya +2 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Image current heating on a metal surface due to charged bunches
When charged particles pass through a metal pipe, they are accompanied by an image current on the metal surface. With intense short bunches passing near or even into the metal surface, the peak image current density can be very high.
Xintian E. Lin, David H. Whittum
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Transient current technique for charged traps detection in silicon bonded interfaces
Wafer bonding is an established technology for the manufacturing of silicon-on-insulator (SOI) substrates, micro-electromechanical systems (MEMS) and microfluidic devices.
J. Bronuzzi +8 more
doaj +1 more source

