Results 41 to 50 of about 1,665,081 (290)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Prospects for Charged Current Deep-Inelastic Scattering off Polarized Nucleons at a Future Electron-Ion Collider

, 2013
We present a detailed phenomenological study of charged-current-mediated deep-inelastic scattering off longitudinally polarized nucleons at a future Electron-Ion Collider.
Aschenauer, Elke C., Burton, Thomas, Martini, Till, Spiesberger, Hubert, Stratmann, Marco   +4 more
core   +1 more source

Transport study of charged current interactions in neutrino-nucleus reactions [PDF]

, 2006
Within a dynamical transport approach we investigate charged current interactions in neutrino-nucleus reactions for neutrino energies of 0.3 - 1.5 GeV with particular emphasis on resonant pion production channels via the $\Delta_{33}(1232)$ resonance ...
Adler, Alvarez-Ruso, Barish, Bass, Bleicher, Campbell, Casper, Cassing, Cassing, Cassing, Cassing, Cassing, Cassing, Effenberger, Effenberger, Ehehalt, Falter, Falter, Feynman, Gallagher, Garvey, Golubeva, Hayato, K. Langanke, Kitagaki, Lehr, Lehr, Lehr, Lehr, Leitner, Leitner, M. Kant, Messchendorp, Mühlich, P. Vogel, Paschos, Paschos, Paschos, Peters, Radecky, Rein, Schreiner, W. Cassing, Wolf, Wolf, Zeller, Zeller   +46 more
core   +2 more sources

Semiclassical dynamics and nonlinear charge current [PDF]

Frontiers of Physics, 2019
Electron conductivity is an important material property that can provide a wealth of information about the underlying system. Especially, the response of the conductivity with respect to electromagnetic fields corresponds to various nonlinear charge currents, which have distinct symmetry requirements and hence can be used as efficient probes of ...
openaire   +3 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Neutrino Magnetic Moment Solution for the Solar Neutrino Problem and the SNO Experiment

, 2000
The motivations for the magnetic moment solution to the solar neutrino problem are briefly reviewed and the expected values for a number of observables to be measured by the SNO experiment are calculated assuming three different solar magnetic field ...
Akhmedov, Akhmedov, Akhmedov, Bahcall, Bahcall, Blinnikov, Blinnikov, Castellani, Fujikawa, Gonzalez-Garcia, Guzzo, João Pulido, Lim, Parker, Pulido, Raffelt, Raffelt, Schechter, Schechter   +18 more
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Search for Charged Current Coherent Pion Production on Carbon in a Few-GeV Neutrino Beam

, 2008
The SciBooNE Collaboration has performed a search for charged current coherent pion production from muon neutrinos scattering on carbon, \nu_\mu ^{12}C \to \mu^- ^{12}C \pi^+, with two distinct data samples.
A. D. Russell, A. Hanson, A. Heikkinen, A. J. Franke, A. A. Belkov, A. A. Belkov, C. D. Moore, C. Giganti, C. Mariani, D. A. Finley, D. Orme, D. Rein, E. D. Zimmerman, F. Sanchez, G. Cheng, G. Jover-Manas, G. Karagiorgi, G. Mills, G. Mitsuka, G. P. Zeller, H. Kubo, H. Takei, H. White, H.-K. Tanaka, I. J. Taylor, J. Birks, J. Catala-Perez, J. J. Gomez-Cadenas, J. J. Walding, J. L. Alcaraz-Aunion, J. M. Conrad, K. B. M. Mahn, K. Hiraide, K. Matsuoka, K. Nitta, K. S. Kuzmin, L. Bugel, L. Ludovici, M. H. Shaevitz, M. J. Wilking, M. O. Wascko, M. Otani, M. Sorel, M. Tanaka, M. Yokoyama, P. F. Loverre, P. Guzowski, P. Nienaber, R. J. Stefanski, R. J. Tesarek, R. Napora, R. Tayloe, R. Van de Water, R. A. Smith, S. J. Brice, S. Masuike, S. Mizugashira, S. S. Gershtein, S. S. Gershtein, T. Katori, T. Kobilarcik, T. Nakaya, T.-A. Shibata, U. Dore, V. Nguyen, W. C. Louis, W. Metcalf, Y. Hayato, Y. K. Kobayashi, Y. Kurimoto, Y. Miyachi, Y. Nakajima, Y. Uchida, Z. Djurcic   +73 more
core   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source