Results 51 to 60 of about 152,917 (265)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Control of Electrostatic Charge on Particles by Impact Charging [PDF]

open access: yesJournal of the Society of Powder Technology, Japan, 2006
The control of electrostatic charge on particles in gas–solids pipe flow has been studied experimentally and theoretically. Alumina particles of 3.3 μm in count median diameter were dispersed in airflow and pneumatically transported in the dilute phase.
Matsusaka, Shuji   +2 more
openaire   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Frictional cooling of positively charged particles

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2012
One of the focuses of research and development towards the construction of a muon collider is muon beam preparation. Simulation of frictional cooling shows that it can achieve the desired emittance reduction to produce high-luminosity muon beams. We show
Daniel Greenwald, Allen Caldwell
doaj   +1 more source

On fast charged particles scattering in a thin crystalline undulator

open access: yesPhysics Letters B, 2019
The scattering of fast charged particles in a thin silicon crystalline undulator is considered under conditions when all the particles of the beam undergo above-barrier motion with respect to the bent crystalline atomic planes. The consideration is based
N.F. Shul'ga, V.I. Truten'
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

DIFFRACTIVE SCATTERING OF CHARGED PARTICLES

open access: yesВестник. Серия физическая, 2010
Studied the scattering of nucleons on nucleons at high energies; studied the angular dependence under the elastic scattering of hadrons. In details considered the scattering of nucleons by deuterons.
E.I. Ismatov, J.K. Ubaev
doaj  

Mean volume reflection angle

open access: yesPhysical Review Accelerators and Beams, 2020
The mean volume reflection angle of a high-energy charged particle passing through a bent crystal is expressed as an integral involving the effective interplanar potential over a single crystal period.
M. V. Bondarenco
doaj   +1 more source

Home - About - Disclaimer - Privacy