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Direct and Indirect Probes for Composite Dark Matter

Frontiers in Physics, 2019
Dark matter candidates are one of the profound signatures of new physics, reflecting existence of new stable particles. If such particles are charged they can bind with ordinary electrons, forming anomalous isotopes.
Maxim Y. Khlopov, Maxim Y. Khlopov, Maxim Y. Khlopov +2 more
doaj +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős +2 more
wiley +1 more source

Experimental evidence of reduced sticking of nanoparticles on a metal grid [PDF]

, 2009
Filtering of NaCl, CaCl2, (NH4)2SO4 and NiSO4 aerosol particles 7–20 nm in diameter by a stainless steel grid was studied in order to find out if there is perfect sticking or partial rebound. Our experiment used particles from a spray-drying process, the
Gulijk, C. van +5 more
core +1 more source

Pseudorapidity densities of charged particles with transverse momentum thresholds in pp collisions at √ s = 5.02 and 13 TeV

, 2023
The pseudorapidity density of charged particles with minimum transverse momentum (pT) thresholds of 0.15, 0.5, 1, and 2 GeV/c is measured in pp collisions at the center of mass energies of √s=5.02 and 13 TeV with the ALICE detector. The study is carried
Ewa Glimos +499 more
core +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel +2 more
wiley +1 more source

Wet electrostatic scrubbing for high efficiency submicron particle capture [PDF]

, 2011
Exposure to fine particulate matter has been associated with serious health effects, including respiratory and cardiovascular disease, and mortality.
D'Addio, Luca
core +1 more source

On magnetic guidance of charged particles

Physics Letters B, 2016
High precision beta decay experiments with polarized neutrons, employing magnetic guiding fields for the decay electrons in combination with energy dispersive detectors, initiated detailed studies of the point spread function (PSF) for homogeneous ...
H. Backe
doaj +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

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physics

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astrophysics
proton therapy

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7. clean energy
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