Results 61 to 70 of about 241,615 (254)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Regional EV Charging Load Forecasting Based on SCLD and FCW

open access: yesWorld Electric Vehicle Journal
Against the backdrop of global energy transition and the continuous growth in electric vehicle (EV) market penetration, accurate forecasting of EV charging load is critically important for guaranteeing the safe and stable operation of power grids.
Taoyong Li   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

The Development of a Test Stand for Electric Fuel-Cell Turbocharger Integrity Testing—Part 2: Results

open access: yesEngineering Proceedings
This paper presents the results of a testbench regarding the effects of liquid water content in the turbine stage of a fuel-cell charging system. The testbench simulates the exhaust conditions of a PEM fuel cell to evaluate erosion potential in a single ...
Georgios Karakasis   +3 more
doaj   +1 more source

The role of pickup truck electrification in the decarbonization of light-duty vehicles

open access: yesEnvironmental Research Letters, 2022
Electrification can reduce the greenhouse gas (GHG) emissions of light-duty vehicles. Previous studies have focused on comparing battery electric vehicle (BEV) sedans to their conventional internal combustion engine vehicle (ICEV) or hybrid electric ...
Maxwell Woody   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

High Density Static Charges Governed Surface Activation for Long-Range Motion and Subsequent Growth of Au Nanocrystals

open access: yesNanomaterials, 2019
How a heavily charged metal nanocrystal, and further a dual-nanocrystals system behavior with continuous electron charging? This refers to the electric dynamics in charged particles as well as the crystal growth for real metal particles, but it is still ...
Guoxin Chen   +7 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

V2G Service Blueprint Co-Design: Case Study from Sweden

open access: yesWorld Electric Vehicle Journal
Vehicle-to-Grid (V2G) is increasingly recognized as a promising source of flexibility for low-carbon energy systems, yet its deployment remains limited in practice.
Elena Malakhatka   +4 more
doaj   +1 more source

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