Results 61 to 70 of about 67,793 (197)

Preoperative Immunotherapy in Hepatocellular Carcinoma: Current State of the Art

Journal of Hepatocellular Carcinoma, 2023
Alena Laschtowitz,1 Christoph Roderburg,2 Frank Tacke,1 Raphael Mohr1 1Department of Hepatology and Gastroenterology, Charité – Universitätsmedizin Berlin, Campus Virchow Klinikum (CVK) and Campus Charité Mitte (CCM), Berlin, Germany; 2Clinic for ...
Laschtowitz A, Roderburg C, Tacke F, Mohr R   +3 more
doaj  

Maximal use of 0.05% topical isotretinoin in patients with congenital ichthyosis results in low systemic exposure

British Journal of Clinical Pharmacology, EarlyView.
Abstract Congenital ichthyoses (CI) are rare, inherited skin disorders characterized by hyperkeratosis, scaling and fissuring that significantly impair patients' quality of life. Treatment options are limited, with systemic retinoids reserved for severe cases owing to their adverse effect profile.
Holm Schneider, Christopher G. Bunick, Kathrin Hillmann, Thy N. Huynh, Steven Kempers, Nicolai Peschel, Ulrike Blume‐Peytavi, Joyce M. C. Teng, Alan M. Mendelsohn, John Stinson, Lara Wine Lee   +10 more
wiley   +1 more source

Non-Invasive Imaging Biomarkers to Predict the Hepatopulmonary Shunt Fraction Before Transarterial Radioembolization in Patients with Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2023
Charlie Alexander Hamm,1,2,* Felix Busch,1,3,* Anna Pöhlmann,4 Annabella Shewarega,5 Yubei He,1 Robin Schmidt,1 Han Xu,1 Gero Wieners,1 Bernhard Gebauer,1 Lynn Jeanette Savic1,2 1Department of Radiology, Campus Virchow-Klinikum, Charité ...
Hamm CA, Busch F, Pöhlmann A, Shewarega A, He Y, Schmidt R, Xu H, Wieners G, Gebauer B, Savic LJ   +9 more
doaj  

Le paradoxe de la règle et les limites du relativisme

Tracés, 2007
Wittgenstein a soutenu l’idée qu’aucun fait mental ne pouvait garantir que le comportement d’un sujet soit l’application d’une règle donnée. Saul Kripke a proposé une version sceptique de cet argument qui vise à faire clairement apparaître en quel sens ...
Sacha Bourgeois-Gironde
doaj   +1 more source

Learning with Patient Campaigners About a German Drug Scandal

Berichte zur Wissenschaftsgeschichte, EarlyView.
The West German drug Duogynon was internationally marketed as a “hormone pregnancy test” (HPT) between the 1950s and 1980s. In the late 1960s it came under suspicion for inducing miscarriage, spina bifida, and a spectrum of birth defects similar to those caused by the sedative thalidomide.
Jesse Olszynko‐Gryn, Anja Suter, Edmund Bolger, Birgit Nemec   +3 more
wiley   +1 more source

When Treatment of Pulmonary Emphysema with Endobronchial Valves Did Not Work: Evaluation of Quantitative CT Analysis and Pulmonary Function Tests Before and After Valve Explantation

International Journal of COPD, 2022
Jonas Alexander Leppig,1 Lan Song,2 Dorothea C Voigt,1 Felix W Feldhaus,1 Christoph Ruwwe-Gloesenkamp,3 Jacopo Saccomanno,3 Bianca C Lassen-Schmidt,4 Konrad Neumann,5 Katja Leitner,6 Ralf H Hubner,3 Felix Doellinger1 1Department of Radiology, Charité ...
Leppig JA, Song L, Voigt DC, Feldhaus FW, Ruwwe-Gloesenkamp C, Saccomanno J, Lassen-Schmidt BC, Neumann K, Leitner K, Hubner RH, Doellinger F   +10 more
doaj  

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Protocol of the follow-up of patients with transthyretin amyloid cardiomyopathy by multimodality imaging (FAITH) study: a prospective observational study in patients with ATTR-CM undergoing treatment with tafamidis

BMJ Open
Introduction This prospective observational study of patients with transthyretin amyloid cardiomyopathy (ATTR-CM) undergoing treatment with tafamidis aims at identifying quantitative image markers and comparing imaging modalities regarding the follow-up ...
Bettina Heidecker, Jeanette Schulz-Menger, Ingolf Sack, Carsten Schwenke, Jan Gröschel, Gina Barzen, Jasmin Zernikow, Edyta Blaszczyk, Katrin Hahn, Helena F Pernice, Elena Romero Dorta, Phillip van Dijck, Sebastian Spethmann   +12 more
doaj   +1 more source

Real‐world characteristics and treatment of cardiac transthyretin amyloidosis: A multicentre, observational study

ESC Heart Failure, Volume 12, Issue 2, Page 1203-1216, April 2025.
The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies, Svenja Ney, Ingrid Kindermann, Yvonne Bewarder, Angela Zimmer, Fabian Knebel, Katrin Hahn, Sebastian Spethmann, Peter Luedike, Lars Michel, Tienush Rassaf, Maria Papathanasiou, Stefan Störk, Vladimir Cejka, Amin Polzin, Fabian Voss, Malte Kelm, Bernhard Unsöld, Christine Meindl, Michael Paulus, Ali Yilmaz, Bishwas Chamling, Caroline Morbach, Roman Pfister   +23 more
wiley   +1 more source

N-Methyl-D-Aspartate Receptor Antibodies in Herpes Simplex Encephalitis

Pediatric Neurology Briefs, 2013
Researchers at Charite University Medicine Berlin, and other centers in Germany, Spain and the US performed a retrospective analysis of 44 patients with polymerase chain reaction-proven herpes simplex encephalitis (HSE) for the presence of onconeuronal ...
J Gordon Millichap
doaj   +1 more source