Results 11 to 20 of about 9,237 (130)

Isatuximab plus carfilzomib and dexamethasone in patients with relapsed multiple myeloma based on prior lines of treatment and refractory status: IKEMA subgroup analysis. [PDF]

open access: yesAm J Hematol, 2023
American Journal of Hematology, Volume 98, Issue 1, Page E15-E19, January 2023.
Dimopoulos MA   +17 more
europepmc   +2 more sources

Efficacy of a benzothiazole-based LRRK2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis. [PDF]

open access: yesCNS Neurosci Ther
Methodology of selection of a LRRK2 inhibitor effective in OPC proliferation, differentiation, and in a murine model of multiple sclerosis. Abstract Aims Multiple sclerosis (MS) is a chronic neurological disease that currently lacks effective curative treatments.
Benítez-Fernández R   +8 more
europepmc   +2 more sources

Reproducibility in the absence of selective reporting: An illustration from large-scale brain asymmetry research. [PDF]

open access: yesHum Brain Mapp, 2022
Region‐wise effect sizes and reproducibility rates of hemispheric asymmetry effects. In general, effects with higher effect sizes showed higher reproducibility, given the same conditions (e.g., sample size and data heterogeneity). Abstract The problem of poor reproducibility of scientific findings has received much attention over recent years, in a ...
Kong XZ   +2 more
europepmc   +2 more sources

From rivers to ocean basins: The role of ocean barriers and philopatry in the genetic structuring of a cosmopolitan coastal predator

open access: yesEcology and Evolution, Volume 13, Issue 2, February 2023., 2023
In this study, 922 putative Bull Sharks were obtained from 19 locations for the first global assessment of population structure of this cosmopolitan coastal species. Nuclear DNA identified distinct populations in each ocean basin, with distinct island populations in Japan and Fiji.
Floriaan Devloo‐Delva   +36 more
wiley   +1 more source

Breeding origins of a uniquely regular migrant songbird in the Galápagos Islands

open access: yesEcology and Evolution, Volume 13, Issue 1, January 2023., 2023
Little is known about the causes and consequences of alternative pathways flown by long‐distance migratory birds. Using population genetic analyses, we compared samples from migratory Bobolinks stopping over in Galapagos with samples from seven locations across their breeding distribution to determine the migrant's breeding population of origin ...
Noah Perlut   +4 more
wiley   +1 more source

In‐field genetic stock identification of overwintering coho salmon in the Gulf of Alaska: Evaluation of Nanopore sequencing for remote real‐time deployment

open access: yesMolecular Ecology Resources, Volume 22, Issue 5, Page 1824-1835, July 2022., 2022
Abstract Genetic stock identification (GSI) from genotyping‐by‐sequencing of single nucleotide polymorphism (SNP) loci has become the gold standard for stock of origin identification in Pacific salmon. The sequencing platforms currently applied require large batch sizes and multiday processing in specialized facilities to perform genotyping by the ...
Christoph M. Deeg   +8 more
wiley   +1 more source

Nudging the N170 forward with prior stimulation—Bridging the gap between N170 and recognition potential

open access: yesHuman Brain Mapping, Volume 43, Issue 4, Page 1214-1230, March 2022., 2022
We use a parametric design of forward masking and a focus on individual‐level event‐related potential (ERP) to show that N170 latency can be gradually pushed forward by as much as 100 ms. We also show that the N170 is indistinguishable from the recognition potential component, which is often treated as completely different and studied in a separate ...
Canhuang Luo   +4 more
wiley   +1 more source

Valorization of pineapple peel and poultry manure for clean energy generation

open access: yesFood and Energy Security, Volume 11, Issue 1, February 2022., 2022
Pineapple waste and poultry manure are abundant bioresources constituting gross environmental menace. This study evaluated their valorization into high value‐added biogas and digestate fertilizer for crop and soil improvement. Abstract The quest for renewable energy generation is fast increasing globally due to environmental degradation by fossil fuels.
Samuel O. Dahunsi   +5 more
wiley   +1 more source

Environmental resistance and habitat quality influence dispersal of the saltwater crocodile

open access: yesMolecular Ecology, Volume 31, Issue 4, Page 1076-1092, February 2022., 2022
Abstract Landscape genetics commonly focuses on the effects of environmental resistance on animal dispersal patterns, but there is an emerging focus on testing environmental effects on emigration and settlement choices. In this study, we used landscape genetics approaches to quantify dispersal patterns in the world's largest crocodilian, the saltwater ...
Yusuke Fukuda   +7 more
wiley   +1 more source

Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure

open access: yesHuman Brain Mapping, Volume 43, Issue 1, Page 37-55, January 2022., 2022
Abstract Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main shortcomings of the neuroimaging literature of these disorders are the small sample sizes employed and the heterogeneity of ...
Martine Hoogman   +79 more
wiley   +1 more source

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