Results 61 to 70 of about 7,824,489 (261)

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Sparse and Expandable Network for Google's Pathways

Frontiers in Big Data
IntroductionRecently, Google introduced Pathways as its next-generation AI architecture. Pathways must address three critical challenges: learning one general model for several continuous tasks, ensuring tasks can leverage each other without forgetting ...
Charles X. Ling, Ganyu Wang, Boyu Wang
doaj   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

Soft and Transient Bioelectronics Enabled by Polymer‐Free Ti3C2Tx MXene Hydrogels

Advanced Materials, EarlyView.
We present Ti3C2Tx MXene hydrogel (MXgel) bioelectronics, a soft, flexible, and fully transient platform for high‐fidelity neural recording and stimulation. MXgel bioelectronics exhibit exceptional electrical conductivities, low electrochemical impedances, and high charge injection capacities.
Raghav Garg, Franco A. Laimo, Stefano Ippolito, Prastuti Upadhyay, Spencer R. Averbeck, Dimitris Boufidis, Charles‐Antoine Assenmacher, Dayo O. Adewole, Sai Panigrahy, Bita Soltan Mohammadlou, Lucy Plant, Yuan Zhang, Andrew G. Richardson, Yury Gogotsi, D. Kacy Cullen, Flavia Vitale   +15 more
wiley   +1 more source

Interface‐Mediated Catalysis for Improved Hydrogen Storage in Reactive Hydride Composites

Advanced Materials, EarlyView.
Catalyst–hydride interfaces are engineered in Co@C‐ and Ni@C‐modified 2LiH + MgB2 reactive hydride composites to accelerate hydrogen uptake and release. Multiscale scattering, in‐situ synchrotron radiation powder x‐ray diffraction and density functional theory calculations reveal the structural and electronic origin of the catalytic enhancement ...
Yuanyuan Shang, Pawan Kumar Soni, Han Ge, Weijie Yang, Fahim Karimi, Thi Thu Le, Tamás Simon, Michael Fröba, Jitendra Mata, Joshua King, Hai‐Wen Li, Thomas Klassen, Claudio Pistidda   +12 more
wiley   +1 more source

A brief history of corneal transplantation: From ancient to modern

Oman Journal of Ophthalmology, 2013
This review highlights many of the fundamental concepts and events in the development of corneal transplantation - from ancient times to modern. Tales of eye, limb, and even heart transplantation appear in ancient and medieval texts; however, in the ...
Alexandra X Crawford, Dipika V Patel, Charles NJ McGhee   +2 more
doaj   +1 more source

Colonial Secretary's Office, Bridge and Macquarie Streets, Sydney [picture] /

, 1895
Title from inscriptions.; Condition: Glued to mount, yellowing.; Inscriptions: "Colonial Secretary's Office. 576. Kerry Photo Sydney"--Printed lower left; Photographer's blind stamp lower left.; Part of the collection: Charles Kerry collection of New ...
Kerry, Charles H. (Charles Henry), 1858-1928.
core  

Donor‐Strength‐Driven Evolution From Charge‐Transfer to Polymethine Excited States in CurcBF2 Derivatives

Advanced Optical Materials, EarlyView.
Donor strength governs the excited‐state character and TADF behavior of donor‐acceptor‐donor borondifluoride curcuminoid derivatives. Increasing donor strength drives a transition from charge‐transfer TADF to a zwitterionic polymethine structure with predominantly local excited‐state emission and suppressed TADF.
Anthony D'Aléo, Guillaume Michaluszko, Amandine Coron, Dae‐Hyeon Kim, Alban de Gary, Danillo Valverde, Elena Zaborova, Emilie Couzigné, Lorry Engel, Loïc Mager, Gabriel Canard, Chihaya Adachi, Yoann Olivier, Jean‐Charles Ribierre   +13 more
wiley   +1 more source

Intestinal Incarceration and Strangulation by the Median Ligament of the Urinary Bladder in a Dog

Animals
A 4.5-year-old female spayed, mixed-breed (Beagle X Cavalier King Charles Spaniel) presented with acute onset of vomiting and abdominal pain. The dog had undergone an exploratory celiotomy for comparable symptoms 9 months earlier, with no aetiology ...
Luke Ellis, Arthur House
doaj   +1 more source

Multimodal Locomotion in Insect‐Inspired Microrobots: A Review of Strategies for Aerial, Surface, Aquatic, and Interfacial Motion

Advanced Robotics Research, EarlyView.
This review identifies key design considerations for insect‐inspired microrobots capable of multimodal locomotion. To draw inspiration, biological and robotic strategies for moving in air, on water surfaces, and underwater are examined, along with approaches for crossing the air–water interface.
Mija Jovchevska, Kaushik Jayaram, Nicole Xu   +2 more
wiley   +1 more source