Results 41 to 50 of about 19,817 (200)

Soft Robotic Excretory Care Simulator for Nursing Education: Functional and Perceptual Biomimetics Approach

open access: yesAdvanced Robotics Research, EarlyView.
A soft robotic simulator is developed to replicate the digital removal of feces (DRF), a sensitive yet essential nursing procedure. Integrating soft actuators, sensors, and a realistic rectal model, the simulator balances functional fidelity with perceptual realism. Engineering evaluations and nurse feedback confirm its potential to enhance training in
Shoko Miyagawa   +10 more
wiley   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

Interpreting Monastic Cartularies in Northwest Europe, 900-1200: Thirty Years of Scholarship

open access: yesStudia Historica. Historia Medieval
Since the publication of Les cartulaires in 1993, the study of cartularies has evolved in two main directions: as part of a broader documentary culture and studying regional or textual patterns using digital tools and postmodern approaches.
Robert Berkhofer
doaj   +1 more source

Connecting Concepts of Cultural Landscape and Historic Urban Landscape: The Politics of Similarity

open access: yesBuilt Heritage, 2018
This paper projects the concept of cultural landscapes into the realm of urban conservation in the context of the Historic Urban Landscape (HUL) paradigm.
Ken Taylor
doaj   +1 more source

The Social Context of the Charter: Times and Places of Documentation in Early Medieval Iberia (711-1031)

open access: yesStudia Historica. Historia Medieval, 2023
When and where was a charter written? Whether the scribe prepared it before, during, or after a transaction, on the spot or elsewhere, conditions its standing as historical evidence.
Graham Barrett
doaj   +1 more source

Climate Change is Rewriting the Hydroclimatic Operating Envelope of Mines

open access: yesAdvanced Science, EarlyView.
Climate change is shown to shift the hydroclimatic operating envelope of mines: 16.2% of represented mine locations have already changed Köppen subtype, rising to 42.5% by late century under SSP5‐8.5. Divergent water trajectories are filtered through geology, infrastructure and lifecycle stage, indicating that adaptation requires monitored, scenario ...
Haoxuan Yu   +3 more
wiley   +1 more source

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai   +13 more
wiley   +1 more source

How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang   +4 more
wiley   +1 more source

The development of the concept of architectural heritage conservation and its inspiration

open access: yesBuilt Heritage, 2023
Over recent decades, heritage conservation has developed in concept and scope. This paper uses a systematic literature review approach to collect charters and documents on heritage conservation issued by UNESCO and ICOMOS, divided into two periods ...
Wen Liang   +2 more
doaj   +1 more source

Promoting Healthier Drinking: Evidence From a Vignette Experiment on Contextual and Informational Drivers of Dealcoholized Wine Choices

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci   +4 more
wiley   +1 more source

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