Results 71 to 80 of about 243,283 (319)

Chasing the Trace [PDF]

open access: yesNeuron, 2014
Event memories are stored in hippocampal-cortical networks. In this issue of Neuron, two studies, Cowansage et al. (2014) and Tanaka et al. (2014), tag active cells during memory encoding and optogenetically manipulate the activity of these "engram" cells during subsequent recall to reveal how hippocampal and cortical cell ensembles interact during ...
Santoro, Adam, Frankland, Paul W.
openaire   +2 more sources

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

open access: yesAdvanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui   +9 more
wiley   +1 more source

Le Brun, Annie. Du Trop de réalité. París: Stock, 2000. 317 págs.

open access: yesLiteratura: Teoría, Historia, Crítica, 2001
Ver documento completo en ...
Ivan Padilla Chasing
doaj  

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li   +15 more
wiley   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

open access: yesAdvanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li   +10 more
wiley   +1 more source

Effects of Lure Type on Chase-Related Behaviour in Racing Greyhounds

open access: yesAnimals, 2020
The willingness of racing greyhounds in Australia to chase a mechanical lure on racetracks will affect the longevity of its racing career. Racing greyhounds that fail to chase may be retired from racing at an early age and their fate becomes uncertain ...
Melissa Starling   +2 more
doaj   +1 more source

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du   +18 more
wiley   +1 more source

Chasing The Dragon

open access: yesMarshall Journal of Medicine, 2018
Although rare, toxic leukoencephalopathy (TLE) associated with heroin inhalation have been reported. ‘Chasing the dragon’ may lead to progressive spongiform degeneration of the brain and presents with a large range of neuropsychological sequelae.
Daniel Young Cho   +2 more
doaj   +1 more source

Central Bank Communication and Multiple Equilibria [PDF]

open access: yes
We construct a simple model in which a central bank communicates with money market traders. We demonstrate that there exist multiple equilibria. In one equilibrium, traders truthfully reveal their own information, and by learning this, the central bank ...
Kozo Ueda
core  

...a chasing after the wind (1992) [PDF]

open access: yes, 1992
Alto flute and piano – composed for Erica Egolf – premiered by her, April 1992https://digitalcommons.butler.edu/jca_scores/1059/thumbnail ...
Felice, Frank
core   +1 more source

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