Results 111 to 120 of about 75,730 (262)

Single‐cell atlas of neuroglial dynamics in SNCA‐A53T Parkinson's disease mouse model

Animal Models and Experimental Medicine, EarlyView.
We performed single‐cell RNA sequencing of midbrain and striatal tissues from SNCA‐A53T Parkinson's disease (PD) mice, revealing glia‐enriched PD‐risk gene signatures and disease‐specific subpopulations. Transcriptional dysregulation of key TFs (e.g., Rorb, Foxc1) and enhanced neuroinflammatory signaling (SEMA, CCL, MIF) were identified.
Binqing Qin, Zichu Fu, Xuanxuan Zou, Senmao Chai, Jingjing Weng, Puqing Wang, Xiaodong Sun, Ming Sang   +7 more
wiley   +1 more source

Maternal‐Fetal Administration of Risdiplam Partially Rescues the SMNΔ7 Mouse Model of Spinal Muscular Atrophy

Annals of Neurology, EarlyView.
Objective Spinal muscular atrophy (SMA) is caused by deletions or mutations in the survival motor neuron 1 (SMN1) gene and subsequent reduction in the expression of survival motor neuron (SMN) protein. The disease is characterized by degeneration of α motor neurons and subsequent muscle atrophy.
Emma R. Sutton, Ariane Beauvais, Rebecca Yaworski, Hugh J. McMillan, Rashmi Kothary   +4 more
wiley   +1 more source

Los chat en la enseñanza de la lengua española

Escuela Abierta, 2019
Este artículo analiza la integración de los chat como recurso educativo en el currículo de Lengua Española y Literatura de Enseñanza Secundaria. En él se reflexiona sobre las características del lenguaje que emplean los alumnos en sus conversaciones por ...
Alejandro Gómez Camacho
doaj  

Linear Viscoelastic Behavior of n‐Alkane Diluted Polyethylene Melts: Sorption, Desorption, and Oscillatory Rheometry

Journal of Applied Polymer Science, EarlyView.
This study systematically maps polyolefin dilution dynamics using a homologous series of n‐alkanes. Integrating gravimetric sorption, subsequent controlled desorption, and oscillatory rheometry establishes a precise framework to analyze reduction in viscosity at least for polymer diluent mixtures with polymer concentration > 35% and diluent ...
Ernst Georg Viehböck, Georg Gschwendner, Dario Pindrić, Gunnar Spiegel, Alexander Hammer, Christian Paulik, Gerald Berger‐Weber   +6 more
wiley   +1 more source

Comparative screening accuracy of the Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-Chat-R/F) for early autism spectrum disorder: a systematic review. [PDF]

Fam Med Community Health
Tsen ASF, Bantalani MA, Ab Rahim MN, Amat SZA, Mokti K.   +4 more
europepmc   +1 more source

Lagomorph cranial biomechanics and the functional significance of the unique fenestrated rostrum of leporids

The Anatomical Record, EarlyView.
Abstract The crania of leporid lagomorphs are uniquely fenestrated, including the posterior cranial bones and the lateral portion of the maxilla. The functional significance of the highly fenestrated rostrum has received considerably little attention, despite being absent in other mammalian herbivores with a long rostrum.
Amber P. Wood‐Bailey, Alana C. Sharp
wiley   +1 more source

The Nudge Effect of "Happy to Chat" Badges: Evidence from England. [PDF]

J Happiness Stud
Yen DA, Jang JM, Yang J, Jen MY, Victor C.   +4 more
europepmc   +1 more source

Tooth row allometry in domestic rabbits and nondomestic lagomorphs: Evidence for a decoupling of body and tooth row size changes in evolutionary time

The Anatomical Record, EarlyView.
Domestic rabbits of different body sizes differ disproportionately in the length of their tooth row or the length of their diastema. Abstract In various domestic mammals, smaller breeds tend to have proportionally larger teeth, whereas this is not a universal trend across mammals.
Ursina L. Fasciati, Christine Böhmer, Stefanie Ohlerth, Marcus Clauss   +3 more
wiley   +1 more source

Chat and Instant Messaging Systems (synchronous): Report 2/3

International Review of Research in Open and Distributed Learning, 2002
Ellen Kinsel, Merv Roy, Harley Waldman, Donna (M. M.) Woloschuk, Patrick J. Fahy   +4 more
doaj   +1 more source

Fine-Tuning Large Language Models for Motivational Interviewing in Health Behavior Change: Development and Evaluation Study. [PDF]

JMIR Form Res
Hu R, Yang Y, Yang Y, Kong J, Luo J, Yang W, Chen J, Liu J, Zeng H, Zhang L, Liu Z.   +10 more
europepmc   +1 more source