Advanced Science, EarlyView.Mechanical intelligence reframes bone regeneration as a time‐dependent coupling between material and cellular memory. Biomaterials store and release mechanical history, while cells retain prior cues and remodel the repair niche. Matching these memories to healing stages may guide stage‐specific scaffolds, sensing‐assisted prediction, mechanical dosing,
Jin Tian +8 more
wiley +1 more source
A comparative analysis of the performance of leading large language models on the endodontics section of the dentistry specialization exam in Türkiye. [PDF]
PLoS OneBaşkan B, Başkan HK, Koç N.
europepmc +1 more source
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Advanced Science, EarlyView.Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
Evaluating chat generative pre-trained transformer responses to common patient questions on temporomandibular disorders. [PDF]
Rev Assoc Med Bras (1992)Unuvar BS, Unuvar EEO.
europepmc +1 more source
Advanced Science, EarlyView.NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source
Large Language Models Utility for Rapid On-Site Evaluation in Interventional Pulmonology. [PDF]
Diagnostics (Basel)Flaschner M +10 more
europepmc +1 more source
Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies
Advanced Science, EarlyView.Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi +5 more
wiley +1 more source
Comparing the Accuracy of ChatGPT-4o, DeepSeek-V3, and Gemini 2.5 Flash in Answering Frequently Asked Questions About Systemic Lupus Erythematosus: Quantitative Study. [PDF]
JMIR Form ResWidhani A +13 more
europepmc +1 more source
Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective
Advanced Science, EarlyView.Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang +11 more
wiley +1 more source