Results 51 to 60 of about 5,553,839 (283)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Le billet à domicile, cet ancêtre insoupçonné du chèque

open access: yesCahiers Jean Moulin
Although the check was mainly designed for individuals and its banking institutionalization significantly emancipates it from exchange rules, this payment instrument is one of the “survivor” among commercial papers.
Vincent Gobin
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Pairwise Check Decoding for LDPC Coded Two-Way Relay Block Fading Channels [PDF]

open access: yes, 2012
Partial decoding has the potential to achieve a larger capacity region than full decoding in two-way relay (TWR) channels. Existing partial decoding realizations are however designed for Gaussian channels and with a static physical layer network coding ...
Jianquan Liu   +4 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Exploration of Refined Teaching Management in Cerebrovascular Surgery of the Grade A Tertiary Hospitals

open access: yesZhongguo cuzhong zazhi
: With the intensification of population aging in China, the incidence of cerebrovascular diseases is increasing year by year, and the demand for cerebrovascular surgery professionals is also getting higher.
LIU Yijie
doaj   +1 more source

The Check-Up, April-June 2013 [PDF]

open access: yes, 2013
An update on issues and ideas related to health reform in Iowa Second Story Headline The Check-Up is a monthly health care reform newsletter designed to keep interested Iowans up to date on the progress of health reform initiatives assigned to ...

core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

A study to determine if estrogen (E) is needed to induce de novo progesterone (P) receptors on gamma/delta t cells as evidenced by determining the degree of rise of progesterone induced blocking factor (PIBF) following P exposure in males

open access: yesClinical and Experimental Obstetrics & Gynecology, 2020
Purpose: To determine if exposure to progesterone (P) alone without prior estrogen (E) exposure can cause a rise in serum progesterone induced blocking factor (PIBF).
J.H. Check   +4 more
doaj   +1 more source

Checking the reality check

open access: yesTrends in Ecology & Evolution, 2010
Let us be clear at the outset that we fully support efforts to direct new plantations away from forests, and our designer landscapes proposal is not a mutually exclusive alternative. Let us also be clear that the history of oil palm expansion, as well as its future (based on current land-use designations), has been and will continue to be the ...
Ghazoul, J.   +2 more
openaire   +2 more sources

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