Results 171 to 180 of about 226,393 (319)

Galactic Chemical Abundances atz > 3. I. First Results from the Echellette Spectrograph and Imager [PDF]

, 2001
J. X. Prochaska, Eric Gawiser, Arthur M. Wolfe   +2 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Determination of the ¹⁵N chemical shift anisotropy in natural abundance samples by proton‐detected 3D solid‐state NMR under ultrafast MAS of 70 kHz

, 2019
Federica Rossi, Nghia Tuan Duong, Manoj Kumar Pandey, Michele R. Chierotti, Roberto Gobetto, Yusuke Nishiyama   +5 more
openalex   +2 more sources

Chemical Abundances in Wolf-Rayet Ring Nebulae: Implications for Nucleosynthesis and Stellar Evolution [PDF]

, 1993
C. Esteban
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Abundance analysis of chemically depleted post-AGB/post-RGB binaries with faint discs [PDF]

Maksym Mohorian, D. Kamath, M. G. K. Menon, H. Van Winckel, Mingjie Jian, A. M. Amarsi, Kateryna D. Andrych   +6 more
openalex   +1 more source

Chemical feature of Eu abundance in the Draco dwarf spheroidal galaxy [PDF]

, 2015
Takuji Tsujimoto, Miho N. Ishigaki, Toshikazu Shigeyama, Wako Aoki   +3 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

A bayesian-like approach to derive chemical abundances in type-2 active galactic nuclei based on photoionization models [PDF]

, 2019
E. Pérez‐Montero, O. L. Dors, J. M. Vı́lchez, R. García-Benito, M. V. Cardaci, G. F. Hägele   +5 more
openalex   +1 more source