Results 171 to 180 of about 4,372,191 (364)

The First Chemical Census of the Milky Way’s Nuclear Star Cluster

open access: yesThe Astrophysical Journal Letters
An important step in understanding the formation and evolution of the nuclear star cluster (NSC) is to investigate its chemistry and chemical evolution. Additionally, exploring the NSC’s relationship to the other structures in the Galactic center and the
Govind Nandakumar   +6 more
doaj   +1 more source

The Sunburst Arc with JWST. III. An Abundance of Direct Chemical Abundances

open access: yesThe Astrophysical Journal
Abstract We measure the gas-phase abundances of the elements He, N, O, Ne, S, Ar, and Fe in an individual H ii region known to be leaking Lyman-continuum photons in the Sunburst Arc, a highly magnified galaxy at redshift z = 2.37. We detect the temperature-sensitive auroral lines [S ii] λλ4070, 4076, [O iii] λ4363, [S ...
Brian Welch   +13 more
openaire   +3 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Tracking the Chemical Evolution of Hydrocarbons Through Carbon Grain Supply in Protoplanetary Disks

open access: yesThe Astrophysical Journal
The gas present in planet-forming disks typically exhibits strong emission features of abundant carbon and oxygen molecular carriers. In some instances, protoplanetary disks show an elevated C/O ratio above interstellar values, which leads to a rich ...
Eshan Raul   +2 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

What Can We Learn from the Nitrogen Abundance of High-z Galaxies?

open access: yesThe Astrophysical Journal
We present measurements of the gas-phase oxygen and nitrogen abundances obtained by applying the direct method to JWST NIRspec R  ∼ 1000 spectroscopy for six galaxies at redshift greater than 3.
Massimo Stiavelli   +11 more
doaj   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Novae: An Important Source of Lithium in the Galaxy

open access: yesThe Astrophysical Journal
The source of the Galactic lithium (Li) has long been a puzzle. With the discovery of Li in novae, extensive research has been conducted. However, there still exists a significant disparity between the observed abundance of Li in novae and the existing ...
Jun Gao   +6 more
doaj   +1 more source

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