Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Relationship between ices and gas phase organic compounds in simulated extraterrestrial environments. [PDF]
Javelle T +5 more
europepmc +1 more source
Baade's window with APOGEE: Metallicities, ages and chemical abundances [PDF]
M. Schultheis +25 more
openalex +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Metagenomic, metabolomic, and sensorial characteristics of fermented <i>Coffea arabica</i> L. var. Castillo beans inoculated with microbial starter cultures. [PDF]
Madrid-Restrepo MA +4 more
europepmc +1 more source
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Origin of Earth's hydrogen and carbon constrained by their core-mantle partitioning and bulk Earth abundance. [PDF]
Tsutsumi Y +6 more
europepmc +1 more source
An idea of designing novel sensors is proposed by creating appropriate Schottky barriers and vacancies between isomorphous Core‐CuOii/ Shell‐CuOi secondary microspheres and enhancing catalytic and spill‐over effects, and electronegativity via spontaneous biphasic separation, self‐assembly, and trace‐Ni‐doping.
Bala Ismail Adamu +8 more
wiley +1 more source
Chemical abundances in main-sequence stars in open cluster M67
Nemo van den Brink
openalex +1 more source
THE SPLASH SURVEY: INTERNAL KINEMATICS, CHEMICAL ABUNDANCES, AND MASSES OF THE ANDROMEDA I, II, III, VII, X, AND XIV DWARF SPHEROIDAL GALAXIES, [PDF]
Jason S. Kalirai +9 more
openalex +1 more source

