Results 51 to 60 of about 852,367 (264)

Synthesis, Purification, and Characterization of Carbon Dots from Non-Activated and Activated Pyrolytic Carbon Black

Nanomaterials, 2022
In this work, carbon dots were created from activated and non-activated pyrolytic carbon black obtained from waste tires, which were then chemically oxidized with HNO3.
Reyna Berenice González-González, Lucy Teresa González, Marc Madou, César Leyva-Porras, Sergio Omar Martinez-Chapa, Alberto Mendoza   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Chemical substructures that enrich for biological activity [PDF]

Bioinformatics, 2008
Abstract Motivation: Certain chemical substructures are present in many drugs. This has led to the claim of ‘privileged’ substructures which are predisposed to bioactivity. Because bias in screening library construction could explain this phenomenon, the existence of privilege has been controversial. Results: Using diverse
Justin Klekota, Frederick P. Roth
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Chemical interactions in active droplets

The Journal of Chemical Physics
Active droplets serve as simple artificial model systems to elucidate the chemical and hydrodynamics-driven interactions between biological organisms. We investigate the pairwise interactions between such micellar solubilization based active droplets, capable of self-generating chemical and hydrodynamic fields.
Prateek Dwivedi, Sobiya Ashraf, Pawan Kumar, Dipin Pillai, Rahul Mangal   +4 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Biomass derived carbon materials: Synthesis and application towards CO2 and H2S adsorption

Nano Select, 2022
Porous carbon materials derived from palm date seeds, guava seeds and winged beans are proposed as environmentally friendly and efficient adsorbents for CO2 and H2S adsorption. The feedstock is converted into hydrochar via hydrothermal carbonization (HTC)
Sabina A. Nicolae, Julian Louis‐Therese, Sarra Gaspard, Petra Ágota Szilágyi, Maria Magdalena Titirici   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

chemical activation

, 2014
Citation: 'chemical activation' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C01017 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Chemically Fueled Active Transport

Angewandte Chemie International Edition
Abstract Biology uses chemical potential differences from molecules like ATP to drive membrane pumps, transporting molecules across membranes even against concentration gradients. Here, we report a synthetic system that transports small molecules from an aqueous phase (the sender) to an aqueous receiver across a centimeter‐sized ...
Christine M. E. Kriebisch, Brigitte A. K. Kriebisch, Gregor Häfner, Héctor Soria‐Carrera, Yanyan Fei, Marcus Müller, Job Boekhoven   +6 more
openaire   +3 more sources