Results 71 to 80 of about 496,469 (302)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2011 100學年度研究獎補助論文The modified correlation equation for predicting the permeate flux of membrane ultrafiltration (UF) in hollow-fiber modules was derived from the complete momentum balance coupled with the application of exponential model.
葉和明, Yeh, H.M.
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Efficient numerical schemes for multidimensional population balance models
Multidimensional population balance models (PBMs) describe chemical and biological processes having a distribution over two or more intrinsic properties (such as size and age, or two independent spatial variables).
Braatz, Richard D, Inguva, Pavan K
core +1 more source
New Construction of Optimum Chemical Balance Weighing Designs
, 1987 The present paper deals with certain chemical balance weighing designs. The incidence matrices of BIB designs for v treatments have been used to construct these designs for p = v + 1 objects.
B. Ceranka, K. Katulska
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2011 Lattice Boltzmann method (LBM) is developed for solution of one-dimensional population balance equations (PBEs) with simultaneous growth, nucleation, aggregation and breakage.
Arvind Rajendran +7 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Some observations on the constructions of chemical balance weighing designs
, 2001 The construction of some optimum chemical balance weighing designs from affine μ-resolvable balanced incomplete block (BIB) designs are discussed in the light of a characterization theorem on the parameters of affine μ-resolvable BIB designs as given by ...
Ceranka, Bronisław +2 more
core +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source