Results 61 to 70 of about 1,166,085 (289)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Gut Bacteria Mediate Aggregation Pheromone Release in the Borer Beetle Trigonorhinus sp.

Insects
Gut microbial symbionts are increasingly recognized as key modulators of host insect physiology and behavior, yet their role in pheromone-mediated chemical communication remains insufficiently understood.
Jinyang Dong, Xiang Yao, Yanru Zhang, Xiuhua Wu, Xinhai Liu, Hongbin Zhang, Haiyan Jiang, Jianli Hou, Jie Yan, Jianing Sun   +9 more
doaj   +1 more source

Moment-based analysis of biochemical networks in a heterogeneous population of communicating cells

, 2019
Cells can utilize chemical communication to exchange information and coordinate their behavior in the presence of noise. Communication can reduce noise to shape a collective response, or amplify noise to generate distinct phenotypic subpopulations.
Gonzales, David T., Tang, T-Y Dora, Zechner, Christoph   +2 more
core   +1 more source

The mechano-chemistry of cytoskeletal force generation [PDF]

, 2014
In this communication, we propose a model to study the non-equilibrium process by which actin stress fibers develop force in contractile cells. The emphasis here is on the non-equilibrium thermodynamics, which is necessary to address the mechanics as ...
Garikipati, Krishna, Maraldi, Mirko
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Social environment has a primary influence on the microbial and odor profiles of a chemically signaling songbird

Frontiers in Ecology and Evolution, 2016
Chemical signaling is an underappreciated means of communication among birds, as may be the potential contributions of symbiotic microbes to animal chemical communication in general.
Danielle June Whittaker, Danielle June Whittaker, Nicole M. Gerlach, Samuel P. Slowinski, Kyle P. Corcoran, Andrew D. Winters, Helena A. Soini, Milos V. Novotny, Ellen D. Ketterson, Kevin R. Theis   +9 more
doaj   +1 more source

One Kairomone and Multiple Effects in Daphnia Species—5α-Cyprinol Sulfate Induces Morphological Defenses in the Invasive Species Daphnia lumholtzi

Frontiers in Ecology and Evolution, 2022
Recently, the first chemical cues, which induce defenses in freshwater zooplankton of the genus Daphnia have been identified. Still it is unknown how general these so-called kairomones are and if they are perceived by and thereby benefitting invasive ...
Meike Hahn, Eric von Elert
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Peripubertal exposure to male chemosignals accelerates vaginal opening and induces male-directed odor preference in female mice

Frontiers in Ecology and Evolution, 2015
Reproductive physiology in female mouse is profoundly affected by male odor. A well-known effect of male odor is the acceleration of puberty onset in prepubertal female mice exposed to male urine.
Mélanie eJouhanneau, Camille eGoudet, Chantal eMoussu, Takuya eTashiro, Bruno eBuatois, Kenji eMori, Guila eGanem, Matthieu eKELLER   +7 more
doaj   +1 more source

Bacteria isolated from Bengal cat (Felis catus × Prionailurus bengalensis) anal sac secretions produce volatile compounds potentially associated with animal signaling. [PDF]

, 2019
In social animals, scent secretions and marking behaviors play critical roles in communication, including intraspecific signals, such as identifying individuals and group membership, as well as interspecific signaling.
Cho, Adrienne W, Coil, David A, Davis, Cristina E, Eisen, Jonathan A, Ganz, Holly H, Jospin, Guillaume, McCartney, Mitchell M, Yamaguchi, Mei S, Zaw, Thant H   +8 more
core   +1 more source