Results 91 to 100 of about 5,665,112 (248)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Chemical Literature

, 1962
Quarterly supplement for "the regular journals of the American Chemical Society," containing annotated bibliographies of chemical documentation literature as well as information about meetings, conferences, awards, scholarships, and other news from the ...
American Chemical Society. Division of Chemical Literature., Valeri, Virginia   +1 more
core   +1 more source

Chemical Literature

, 1964
Quarterly supplement for "the regular journals of the American Chemical Society," containing annotated bibliographies of chemical documentation literature as well as information about meetings, conferences, awards, scholarships, and other news from the ...
American Chemical Society. Division of Chemical Literature., Valeri, Virginia   +1 more
core   +3 more sources

Chemical Constituents from Himatanthus articulata

Journal of the Brazilian Chemical Society, 1998
Chemical investigation of Himatanthus articulata (Vahl) Woodson led to the isolation of stigmasterol, sitosterol, cycloartenol, alpha-amyrin-3beta-O-cinnamoyl, beta-amyrin-3beta-O-cinnamoyl, lupeol-3beta-O-cinnamoyl, alpha-amirin-3beta-O-acetyl, beta ...
Barreto Alaide de Sá, Carvalho Mário Geraldo de, Nery Ivanilton de Almeida, Gonzaga Luiz, Kaplan Maria Auxiliadora Coelho   +4 more
doaj  

Chemical Constituents of Pall. From Shaanxi

Natural Product Communications, 2006
A novel amide, qinjiaoamide and a novel iridoid, erythrocentaurin acid, together with seven known compounds [erythrocentaurin ( 3 ), roburic acid ( 4 ), oleanolic acid ( 5 ), gentiopicroside ( 6 ), swertiamarine ( 7 ), sweroside ( 8 ), and 6′-O-β-D ...
Qianliang Chen, Wenji Sun, Guangzhong Tu, Zhangyan Shi, Yongmin Zhang   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

From fermentation to cancer prevention: The anticancer potential of Kombucha

Phytomedicine Plus
Background: Kombucha is a fermented tea with a distinct sweet and sour taste. It is believed to offer several health benefits, including improved digestion, enhanced immune system, detoxification, and potential anticancer activity, which is thought to be
Opik Taupiqurrohman, Lathifah Puji Hastuti, Dina Oktavia, Belal Omar Al-Najjar, Muhammad Yusuf, Yani Suryani, Shabarni Gaffar   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source