Results 191 to 200 of about 5,665,112 (248)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

New chemical constituents of Ambrosia psilostachya

ARKIVOC, 2007
Athar Ata, Courtney Diduck, Chibuike C. Udenigwe, Shamsulhaq Zahid, Andreas Decken   +4 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Research Progress on Chemical Constituents and Pharmacological Effects of Amides From Natural Sources. [PDF]

Chem Biodivers
Yang XF, Su CY, Long QX, You SQ, Liu Y, Wu JY, Meng FH, Luo JH, Yu XY, Liu B, Zhang W.   +10 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Neuroprotective effects of chemical constituents from Nicotiana tabacum L. in Parkinson's disease. [PDF]

Nat Prod Bioprospect
Zang HJ, Bai XL, Sui XY, Zhai XR, Wang YC, Xin ZQ, Yin QY, Hao XJ, Wang YH, Liao X, Di YT.   +10 more
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Chemical Constituents and Pharmacological Effects of <i>Camellia oleifera</i> Fruits: A Review. [PDF]

Molecules
Xu B, Du AN, Liu TZ, Wei PH, Zhu BR, Chen K, Shi L.   +6 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Antimicrobial Activity and Chemical Constituents of Siparuna guianensis (Siparunaceae). [PDF]

Chem Biodivers
Vilanculo OMM, Pinheiro MSDS, de Oliveira LC, de Souza DAA, Cardoso SVD, Silva SDC, Marinho PSB, do Rosario Marinho AM.   +7 more
europepmc   +1 more source