Results 191 to 200 of about 22,873,938 (353)

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Crude toxin production and chemical control of Boeremia exigua. [PDF]

Sci Rep
Zhang P, Zhang W, Wang S, Zhang H, Zhu M, Wu D, Sun Y, Zhang H.   +7 more
europepmc   +1 more source

Response of faba bean to intercropping, biological and chemical control against broomrape and root rot diseases. [PDF]

Saudi J Biol Sci, 2022
El-Mehy AA, El-Gendy HM, Aioub AAA, Mahmoud SF, Abdel-Gawad S, Elesawy AE, Elnahal ASM.   +6 more
europepmc   +1 more source

Computer control of chemical process plants with special reference to distillation

, 1980
Siavash Daie
openalex   +1 more source

Proposal for the teaching of the chemical control of supragingival biofilm [PDF]

, 2010
Rui Vicente Oppermann, Alex Nogueira Haas, German Eduardo Miguel Villoria, Laura Guimarães Primo, Júnia Maria Serra‐Negra, Efigênia Ferreira e Ferreira, Cláudio Mendes Pannuti   +6 more
openalex   +1 more source

Chemical control of flowering time

Journal of Experimental Botany, 2016
I. Ionescu, B. Møller, R. Sánchez-Pérez   +2 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Potential of Essential Oils and Major EO Constituents in the Chemical Control of <i>Spodoptera frugiperda</i>. [PDF]

Plants (Basel)
Usseglio VL, Beato M, Dambolena JS, Zunino MP.   +3 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Diffusion-controlled growth of a planar chemical garden wall before osmotic fracture

Mingchuan Zheng, P. R. L. Welche, Silvana S. S. Cardoso, Herbert E. Huppert, Julyan H. E. Cartwright, Alexander F. Routh   +5 more
openalex   +1 more source