V. Loodts, L. Rongy, A. D. Wit
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Chemical control for the morphogenesis of conducting polymer dendrites in water.
Baron A +5 more
europepmc +1 more source
Chemical control of medically important arthropods in Panama: A systematic literature review of historical efforts. [PDF]
Tuñon A +5 more
europepmc +1 more source
Chemical Control of the Cotton Fleahopper, Plant Bug and Their Effect on Beneficial Insects, 1979 [PDF]
Richard Price +3 more
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Targeted protein degradation in the mitochondrial matrix and its application to chemical control of mitochondrial morphology. [PDF]
Yamada W +4 more
europepmc +1 more source
A Genetic Toggle for Chemical Control of Individual Plk1 Substrates. [PDF]
Johnson JM +7 more
europepmc +1 more source
Conditional Control of CRISPR/Cas9 Function by Chemically Modified Oligonucleotides [PDF]
Liangliang Wang +4 more
openalex +1 more source

