Results 61 to 70 of about 240,894 (296)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Nestmate Recognition in the Amazonian Myrmecophyte Ant Pseudomyrmex concolor Smith (Hymenoptera, Formicidae)

Sociobiology, 2015
Nestmate recognition is fundamental to colonial cohesion in social insects, since it allows altruistic behavior towards relatives, recognition of intruders, territorial monopoly and resources defense.
Kleber Del-Claro, Paulo S.M. Pacheco
doaj   +1 more source

Influence of blood meal on the responsiveness of olfactory receptor neurons in antennal sensilla trichodea of the yellow fever mosquito, Aedes aegypti [PDF]

, 2010
In female Aedes aegypti L. mosquitoes, a blood meal induces physiological and behavioral changes. Previous studies have shown that olfactory receptor neurons (ORNs) housed in grooved peg sensilla on the antennae of Ae.
Hansson, Bill, Hill, Sharon, Ignell, Rickard, Siju, K.P.   +3 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Discrimination and Aggregative Patterns among and between populations of Entamoeba spp. [PDF]

, 2011
Kin recognition facilitates the evolution of cooperation in animals, but its relevance in microorganisms and their behavior toward relatives remains unclear.
Higgins, Katelyn M.
core   +1 more source

Use of habitat odour by host-seeking insects [PDF]

, 2017
Locating suitable feeding or oviposition sites is essential for insect survival. Understanding how insects achieve this is crucial, not only for understanding the ecology and evolution of insect–host interactions, but also for the development of ...
Afsheen, Alagarmalai, Baldacchino, Bau, Becker, Bell, Beyaert, Birkett, Boyle, Bruce, Bruce, Bukovinszky, Calatayud, Cardé, Cardé, Chapman, Cooperband, Cooperband, De Moraes, Dekker, Faucher, Goubert, Hagen, Hare, Heil, Held, Hilker, Johnson, Johnson, Johnson, Kissling, Koehl, Lacey, Lacey, Legaspi, Lehane, Li, Lihoreau, Lorenz, Manoukis, McCormick, McMeniman, Meiners, Moreau, Moreno, Muller, Murlis, Murlis, Mwenda, Negro, Nevitt, Nordéus, Payne, Pickett, Pierik, Potts, Randlkofer, Reinecke, Rijk, Rogers, Rogers, Ruther, Saveer, Schröder, Soni, Spitzen, Spitzen, Tauxe, Turner, Vaidyanathan, Vet, Voskamp, Webster, Webster, Webster, Webster, Webster, Zöllner   +77 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Effect of Grazing-Mediated Dimethyl Sulfide (DMS) Production on the Swimming Behavior of the Copepod Calanus helgolandicus [PDF]

, 2013
Chemical interactions play a fundamental role in the ecology of marine foodwebs. Dimethyl sulfide (DMS) is a ubiquitous marine trace gas that acts as a bioactive compound by eliciting foraging behavior in a range of marine taxa including the copepod ...
Bode, Nikolai, Breckels, Mark, Codling, Edward, Steinke, Michael   +3 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source