Results 51 to 60 of about 947,503 (258)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Master's degree in Chemical Engineering
, 2023 Chemical engineering is directly concerned with obtaining various products (fuels, solvents, medicines, paints, plastics, detergents, etc.) and services (water and energy supply, waste management and valorisation, etc.) that ensure our quality of life ...
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Department of Chemical and Biological Engineering newsletter Fall 2019
, 2019 Occasionally called "The EXTRACT: a newsletter for friends and ...
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Multi-Objective Optimization Applications in Chemical Engineering
, 2013 10.1002/9781118341704.ch3Multi-Objective Optimization in Chemical Engineering: Developments and Applications35 ...
Shivom Sharma +3 more
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Nonsmooth differential-algebraic equations in chemical engineering
, 2018 This article advocates a nonsmooth differential-algebraic equations (DAEs) modeling paradigm for dynamic simulation and optimization of process operations.
Patrascu, Michael +5 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Systems biology approaches for chemical engineering [PDF]
, 2011 Biological systems are becoming of central interest also in fields which go beyond science and medicine scopes, such as chemical engineering. In the last decades, some complex biological systems have been considered for large scale chemicals production ...
Gatto, Fancesco
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