Results 81 to 90 of about 947,503 (258)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Chemical engineering prospective; chemical product engineering

آموزش مهندسی ایران, 2019
It is less than 20 years that the concept of chemical product engineering and chemical product engineer is introduced by chemical engineers. The concept is introduced by US universities and followed by the EU universities afterward. They have introduced the chemical product engineering course at BSc and MSc levels.
openaire   +1 more source

Chemical engineering and chemistry: education in a changing world

, 2006
Current trends in science and engineering research are analyzed, together with an inventory of changes in the field of employment and practice in industry.
Reijenga, JC Jetse, Jetse Reijenga, Reijenga, J.C., Reijenga Jetse C.   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Development of Functional Nanomaterials for Applications in Chemical Engineering. [PDF]

Nanomaterials (Basel), 2023
Cao M.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Design of an oxygen reduction catalyst for direct methanol fuel cells

, 2010
10.1021/ie100524sIndustrial and Engineering Chemistry Research492110251 ...
Yang, J., Saeys, Mark, Yang, Jinhua, Lee, Jim Yang, Lee, J.Y., Jim Yang Lee, Xu, Jing, Jing Xu, Jinhua Yang, Saeys, MarkTW110019933079648010012395360000-0002-3426-6662E147F392-8B94-11E3-91E9-018A10BDE39D, Xu, J., Saeys, M., Mark Saeys   +12 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Emerging chemical engineering of exosomes as "bioscaffolds" in diagnostics and therapeutics. [PDF]

Genes Dis, 2023
Wang J, Wang M, Jiang N, Ding S, Peng Q, Zheng L.   +5 more
europepmc   +1 more source

Experimental and theoretical insight of nonisothermal adsorption kinetics for a single component adsorbent-adsorbate system

, 2012
10.1021/je201210tJournal of Chemical and Engineering Data5741174 ...
Loh, W.S., Loh, Wai Soong, Ng, K.C., Ng, Kim Choon, Saha, B.B., Chakraborty, Anutosh, Saha, Bidyut Baran, Chakraborty, A.   +7 more
core   +1 more source