Results 91 to 100 of about 1,921,756 (289)

Ocular chemical injuries and their management

open access: yesOman Journal of Ophthalmology, 2013
Chemical burns represent potentially blinding ocular injuries and constitute a true ocular emergency requiring immediate assessment and initiation of treatment.
Parul Singh   +4 more
doaj   +1 more source

Development of Fungal Applications on Netting Substrates for Malaria Vector Control [PDF]

open access: yes, 2011
Mosquito resistance to chemical insecticides is considered a serious threat for the sustainable use of contemporary malaria vector control methods.
Farenhorst, M.   +3 more
core   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Wavelet Entropy Based Analysis and Forecasting of Crude Oil Price Dynamics

open access: yesEntropy, 2015
For the modeling of complex and nonlinear crude oil price dynamics and movement, wavelet analysis can decompose the time series and produce multiple economically meaningful decomposition structures based on different assumptions of wavelet families and ...
Yingchao Zou, Lean Yu, Kaijian He
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Lansing K-12 School District: Chemical and Resource Management Services (CRMS) Case Study [PDF]

open access: yes, 2006
Nationwide, public K-12 school districts are being asked to meet increasing educational demandswith diminishing financial resources. At the same time, high-profile hazardous material incidents inschools have made improved chemical management a top ...

core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Estimating Portfolio Value at Risk in the Electricity Markets Using an Entropy Optimized BEMD Approach

open access: yesEntropy, 2015
In this paper, we propose a new entropy-optimized bivariate empirical mode decomposition (BEMD)-based model for estimating portfolio value at risk (PVaR). It reveals and analyzes different components of the price fluctuation.
Yingchao Zou, Lean Yu, Kaijian He
doaj   +1 more source

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