Results 131 to 140 of about 440,588 (304)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Evaluation of Homogeneity from Ore-bodied in Nigeria for Secondary Mineral Prospective [PDF]

open access: yes, 2012
Samples from ore–bodied areas at different locations in Papalanto and Ifo in Ogun-State, South-West of Nigeria, where Ewekoro cement industry is situated, were analyzed so as to recover some secondary minerals of economic value.
Inegbenebor, A. I.   +2 more
core  

Treatment of palm oil mill secondary effluent (POMSE) using ultrafiltration and nanofiltration membranes [PDF]

open access: yes, 2020
Malaysian palm oil industry has grown rapidly over the last few decades, to becoming the world’s largest producer and exporter of palm oil. This success story however, comes with a greater challenge and equally required more sacrifices in order to ...
Ali, Nurmursalina   +4 more
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

PRELIMINARY STUDY ON BIOGAS PRODUCTION OF BIOGAS FROM MUNICIPAL SOLID WASTE (MSW) LEACHATE [PDF]

open access: yesJournal of Engineering Science and Technology, 2009
Laboratory-scale digesters were operated to study the effect of leachate chemical oxygen demand strength on biogas (methane) production. Three sets of experiment were performed using municipal solid waste leachate slurry with two different chemical ...
WAN AZLINA WAN AB KARIM GHANI   +1 more
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Improved greywater quality after biofiltration with a fibre-biofilter derived from plantain pseudo stem

open access: yesScientific African
In this study, we addressed the prevalent issue of untreated greywater discharge into waterbodies in many developing countries, despite the associated public health risks.
Abdul Rahim Mohammed   +2 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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