Results 51 to 60 of about 120,773 (255)

The Effectiveness of Pseudomonas aeruginosa in Degrading Biochemical Oxygen Demand and Chemical Oxygen Demand in Small Island Domestic Wastewater [PDF]

Nature Environment and Pollution Technology
The high organic content of domestic wastewater on small islands increases the risk of environmental pollution and disease spread. Limited resources and infrastructure exacerbate waste management challenges in these regions.
Nurdianti, Agus Bintara Birawida, Hasnawati Amqam, Gurendro Putro and Shaharuddin Mohd Sham
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

New ultrasound assisted chemical oxygen demand determination

Ultrasonics Sonochemistry, 2002
A new method for the chemical oxygen demand (COD) determination assisted by ultrasonic radiation has been evaluated for the first time. The suggested method uses an instrumentation simpler and cheaper than the previous ones used for the same purpose. With this preliminary version of the method the optimized experimental conditions are: high ultrasonic ...
Antonio, Canals, Angel, Cuesta, Luis, Gras, M Remedios, Hernández   +3 more
openaire   +2 more sources

Assessment of Physicochemical Properties and Heavy Metals in Borehole Water Used For Drinking In Okada Town, Edo State, Nigeria

Journal of Applied Sciences and Environmental Management, 2020
The consumption of unsafe water is detrimental to human health. It is therefore important to ascertain the quality and purity of water set out for drinking.
W.A. Raji, C.E. Anih, P.O. Obeta
doaj   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Enhance Removal Pollutant from Batik Industrial Wastewater via Photo- Fenton Process: Efficiency and Kinetic Study

Journal of Chemical Engineering Research Progress
The present research evaluates the efficiency of the Photo-Fenton-like process under UV irradiation by varying ratio of hydrogen peroxide (H₂O₂) to Chemical Oxygen Demand (COD) and H₂O₂ to ferrous ion (Fe²⁺) using wastewater from a batik manufacturer in ...
Oki Setiawan, Siti Adriani, Haposan Vincentius Manalu, Aninditiya Amalia, Ifti Luthviana Dewi, Insan Kamil, Darti Purnama Sari, Popi Sasniati   +7 more
doaj   +1 more source