Results 81 to 90 of about 440,588 (304)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Preliminary Analysis of Load Input into the Accumulation Varaždin by Rain Overflow
Tehnički Glasnik, 2021 The wastewater treatment plant Varaždin upgrade project envisages the reconstruction of the rain overflow directly upstream of the plant. Physicochemical parameters of water quality (Biological Oxygen Demand, Chemical Oxygen Demand, Total Nitrogen, Total
Domagoj Nakić +3 more
doaj
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Effect of dissolved oxygen and chemical oxygen demand to nitrogen ratios on the partial nitrification/denitrification process in moving bed biofilm reactors [PDF]
, 2011 Partial nitrification was reported to be technically feasible and economically favorable, especially for wastewater with high ammonium concentration or low C/N ratio.
Attar, H.M. +4 more
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
The aerobic treatment of reverse osmosis permeate for reuse : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Technology in Environmental Engineering [PDF]
, 1995 The reduction of effluent streams and the demand for freshwater intake in the dairy industry, may be accomplished by the segregation and reuse of streams that can be readily treated.
Bickers, Paul Oliver
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
A Chemical Survey of the Batang Belungkung River and the Gombak River [PDF]
, 1980 A chemical survey of water quality in the Batang Belungkung River and the Gombak River was conducted to assess the degree of pollution due to the continuing discharge of rubber and domestic wastes.
Ng, B. S., Tan, W. T.
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Soil and Water Contamination due to Illegal Artisanal Refinery Activities: A Case Study of Okarki Community, Niger Delta Area, Nigeria [PDF]
, 2019 Using a combination of field visits, laboratory experiments and analyses, this study examined the impacts of illegal artisanal crude oil refineries on the environment. Total Hydrocarbons (THC) and heavy metals in the soil and water bodies as well as pr
Galadima, Muhammed +3 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source