Results 41 to 50 of about 14,188 (258)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Integration of coagulation and electro-activated HSO5− to treat pulp and paper wastewater

Sustainable Environment Research, 2017
Pulp and paper wastewater (PPW) is classified as complex wastewater that contains high concentrations of recalcitrant pollutants. In this study, the integration of coagulation process and electro-activated peroxymonosulfate (PMS) were tested to treat PPW.
Nematollah Jaafarzadeh, Farshid Ghanbari, Mahtab Alvandi   +2 more
doaj   +1 more source

Comparison of Ozone Pre-Treatment and Post-Treatment Hybrid with Moving Bed Biofilm Reactor in Removal of Remazol Black 5

International Journal of Technology, 2021
The purpose of this research is to investigate wastewater treatment with ozone pre-treatment and post-treatment integrated with Moving Bed Biofilm Reactor (MBBR).
I Wayan Koko Suryawan, Iva Yenis Septiariva, Qomarudin Helmy, Suprihanto Notodarmojo, Marita Wulandari, Novi Kartika Sari, Ariyanti Sarwono, Riska Pratiwi, Jun-Wei Lim   +8 more
doaj   +1 more source

Simultaneous Determination of Chemical Oxygen Demand (COD) and Biological Oxygen Demand (BOD5) in Wastewater by Near-Infrared Spectrometry

Journal of Water Resource and Protection, 2009
To rapidly determine the pollution extent of wastewater, the calibration models were established for deter-mination of Chemical Oxygen Demand and Biological Oxygen Demand in wastewater by partial least squares and near infrared spectrometry of 120 samples. Spectral data preprocessing and outliers’ diagnosis were also discussed. Correlation coefficients
Qiong YANG, Zhenyao LIU, Jidong YANG
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Assessment of Physicochemical parameters of Freshwater and Tap Water in Suez Canal Region, Egypt [PDF]

Records of Pharmaceutical & Biomedical Sciences, 2019
The objective of this study was to monitor the freshwater quality in Suez Canal region, Egypt and to determine the efficacy of water treatment system in the removal of contaminates. The hydrographic parameters recorded were air and water temperatures, pH,
Randa Abdel-Salam
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Microbial Fuel Cell-Based Organic Matter Sensors: Principles, Structures and Applications

Bioengineering, 2023
Wastewater contains a significant quantity of organic matter, continuously causing environmental pollution. Timely and accurate detection of organic content in water can facilitate improved wastewater treatment and better protect the environment ...
Huang Yao, Jialong Xiao, Xinhua Tang
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source