Results 41 to 50 of about 252,780 (265)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Phosphorus recovery as vivianite and amorphous calcium phosphate from high-load industrial wastewater

Frontiers in Environmental Science
This study evaluated the recovery of amorphous calcium phosphate and vivianite from industrial wastewater produced by a toothpaste manufacturing facility, where phosphorus concentrations exceed 3,000 mg L−1.
Dyllon G. Randall, Dyllon G. Randall, Dyllon G. Randall, Justus Jalava, Björn Vinnerås, Prithvi Simha   +5 more
doaj   +1 more source

Comparison of Microwave-Assisted Synthesis Routes in the Preparation of SnO2 Nanograins by Chemical Precipitation [PDF]

Philippine E-Journal for Applied Research and Development, 2017
This study considers the effect of microwave treatment in the production of SnO2 nanograins, showing that high-temperature annealing may be omitted in a microwave-assisted process. Tin dioxide nanograins were prepared by chemical precipitation and heated
Maricris C. Cunanan, Evelyn P. Navarro, Rinlee Butch M. Cervera, Erwin C. Escobar   +3 more
doaj  

Sol–Gel Synthesis and Characterization of YSZ Nanofillers for Dental Cements at Different Temperatures

Dentistry Journal, 2021
Background: Yttria-stabilized zirconia nanoparticles can be applied as fillers to improve the mechanical and antibacterial properties of luting cement. The aim of this study was to synthesize yttria-stabilized zirconia nanoparticles by the sol–gel method
Anastasia Beketova, Anna Theocharidou, Ioannis Tsamesidis, Athanasios E. Rigos, Georgia K. Pouroutzidou, Emmanouil-George C. Tzanakakis, Dimitra Kourtidou, Liliana Liverani, Marcela Arango Ospina, Antonios Anastasiou, Ioannis G. Tzoutzas, Eleana Kontonasaki   +11 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Morphology Effects on Electro- and Photo-Catalytic Properties of Zinc Oxide Nanostructures

Nanomaterials, 2023
Environmental problems are among the most pressing issues in the modern world, including the shortage of clean drinking water partially caused by contamination from various industries and the excessive emission of CO2 primarily from the massive use of ...
Yevgeniya Y. Kedruk, Alessandra Contestabile, Juqin Zeng, Marco Fontana, Marco Laurenti, Lesya V. Gritsenko, Giancarlo Cicero, Candido F. Pirri, Khabibulla A. Abdullin   +8 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Technologies and research progress of resource utilization of salt production wastewater

Gongye shui chuli
The resource utilization of salt-making wastewater(bittern) is crucial for the sustainable development of the salt-making industry. This paper systematically summarizes the main technical routes for bittern resource utilization, including membrane ...
QIU Changyi, PENG Ruimin, LIU Chenglin
doaj   +1 more source

SEWAGE PURIFICATION BY SEPTIC TANK AND CHEMICAL PRECIPITATION. [PDF]

Journal of the American Medical Association, 1907
The obvious impossibility of discussing in any detail either the septic tank or chemical treatment of sewage, in the twenty or thirty minutes allotted, makes it necessary that the subject be treated very generally, depending on the discussion which may follow to bring out special points of interest.
openaire   +2 more sources