Results 81 to 90 of about 2,748,561 (267)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

PENGARUH VARIASI PUTARAN TERHADAP EMISI GAS BUANG MOBIL TOYOTA KIJANG 4 LANGKAH 1300 CC DENGAN CATALYTIC CONVERTER DAN TANPA CATALYTIC CONVERTER [PDF]

open access: yes, 2006
Catalytic converter is an important tools to prevent about a pollution problem, wherever this problem every time growth up, why the pollution problem every day growth time ?
WIBOWO, ADI
core  

Syntactic Markovian Bisimulation for Chemical Reaction Networks

open access: yes, 2017
In chemical reaction networks (CRNs) with stochastic semantics based on continuous-time Markov chains (CTMCs), the typically large populations of species cause combinatorially large state spaces.
A Abate   +39 more
core   +1 more source

Novel nano-semiconductor film layer supported nano-Pd Complex Nanostructured Catalyst Pd/Ⓕ-MeOx/AC for High Efficient Selective Hydrogenation of Phenol to Cyclohexanone

open access: yesScientific Reports, 2017
Supported metal as a type of heterogeneous catalysts are the most widely used in industrial processes. High dispersion of the metal particles of supported catalyst is a key factor in determining the performance of such catalysts.
Jiaqi Si   +4 more
doaj   +1 more source

Imaging the node-linker coordination in the bulk and local structures of metal-organic frameworks

open access: yesNature Communications, 2020
Metal-organic frameworks (MOFs) are so sensitive to electron beams that it is challenging to atomically image their structures by electron microscopy. Here, the authors use the integrated differential phase contrast technique in STEM to achieve the low ...
Boyuan Shen   +4 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Process for synthesizing and formulating condensed ring polymers [PDF]

open access: yes, 1972
Chemical process for forming low molecular weight, fully cyclized heteroaromatic prepolymers under conditions which limit chain extension or branching is described. Exact procedures used in conducting chemical reaction are defined.
Hughes, C. T., Mchenry, R. J.
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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