Results 111 to 120 of about 11,619,519 (302)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Ultrasmall single-layered NbSe2 nanotubes flattened within a chemical-driven self-pressurized carbon nanotube

Nature Communications
Pressure can alter interatomic distances and its electrostatic interactions, exerting a profound modifying effect on electron orbitals and bonding patterns.
Yaxin Jiang, Hao Xiong, Tianping Ying, Guo Tian, Xiao Chen, Fei Wei   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Photothermal regulation materials: A comprehensive review of passive radiative cooling, passive solar heating, and dynamic photothermal regulation materials

Review of Materials Research
To address the urgent challenges of global climate change and the energy crisis, photothermal regulation (PTR) technologies, requiring no external energy input and relying solely on the intrinsic photothermal properties of materials, have attracted ...
Shuang Tao, Qixuan Cai, Chang Liu, Weiyin Su, Mengxin Lei, Linan Feng, Ya Huang, Kangkang Wang, Siming Zhao, Zhuojing Zhao, Zhenyu Guo, Yonglu Zang, Rufan Zhang   +12 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Controllable Synthesis of Silver Dendrites via an Interplay of Chemical Diffusion and Reaction

, 2016
Here we report a study on the role of chemical diffusion and reaction on the morphology evolution of silver particles. Electrochemical reaction is employed to synthesize silver particles.
Che, Ping, Liu, Jianmei, Yang, Tao, Liu, Wei, Han, Yongsheng, Tao Yang, Wei Liu, Yongsheng Han, Ping Che, Jianmei Liu   +9 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Molecular design of amphiphilic triblock copolymers as additives for high performance poly(vinyl chloride) ultrafiltration membranes

Scientific Reports
Amphiphilic triblock copolymers (TBCs) of poly(styrene)-b-polyethylene glycol-b-poly(styrene) (PS-b-PEG-b-PS) were synthesized by atom transfer radical polymerization (ATRP) and added to poly(vinyl chloride) (PVC) to prepare ultrafiltration (UF) blend ...
Hasan Alshammari, Maral Ghahramani, Alireza Sharif   +2 more
doaj   +1 more source

Application of chemical reaction engineering principles to 'body-on-a-chip' systems. [PDF]

AIChE J, 2018
Sung JH, Wang YI, Kim JH, Lee JM, Shuler ML.   +4 more
europepmc   +1 more source