Results 111 to 120 of about 335,422 (272)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Signatures of quark gluon plasma formation in high-energy heavy ion collisions : a critical review [PDF]

open access: yes, 2005
Ultra-relativistic heavy ion collisions offer the unique opportunity to probe highly excited dense nuclear matter under controlled laboratory conditions. The compelling driving force for such studies is the expectation that an entirely new form of matter
Bass, Steffen A.   +3 more
core  

A Quick Tour of Ultra-Relativistic Heavy-Ion Physics at the LHC

open access: yes, 2012
A brief summary of results on Pb+Pb collisions from ALICE, ATLAS, and CMS is presented covering global event properties, anisotropic flow, jet quenching, and quarkonia.Comment: 11 pages, 8 figures, plenary talk given at the DIS2012 conference, Bonn ...
Reygers, Klaus
core   +1 more source

Uncertainty-Aware Yield Prediction with Multimodal Molecular Features

open access: yesAAAI Conference on Artificial Intelligence
Predicting chemical reaction yields is pivotal for efficient chemical synthesis, an area that focuses on the creation of novel compounds for diverse uses.
Jiayuan Chen   +4 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Process Design and Optimisation Analysis for the Production of Ultra-High-Purity Phosphine

open access: yesSeparations
With the increasing demand to scale the chip industry, attention is turning to the vital role that phosphanes and silanes play in semiconductor manufacturing processes such as chemical vapor deposition, plasma etching, and impurity doping.
Jingang Wang   +5 more
doaj   +1 more source

Has the Quark-Gluon Plasma been seen?

open access: yes, 2005
Data from the first three years of running at RHIC are reviewed and put into context with data obtained previously at the AGS and SPS and with the physics question of creation of a quark-gluon plasma in high energy heavy ion collisions.
Adamova D.   +7 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PTML models of self assembled ligand free nanoparticle catalysts for cross coupling reactions

open access: yesScientific Reports
Cross-coupling reactions have transformed the synthesis of complex and valuable compounds used in pharmaceuticals, materials science, and chemical synthesis.
Andrea Ruiz-Escudero   +3 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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