Results 71 to 80 of about 335,422 (272)
Prediction of chemical reaction yields with large-scale multi-view pre-training
Journal of CheminformaticsDeveloping machine learning models with high generalization capability for predicting chemical reaction yields is of significant interest and importance.
Runhan Shi +3 more
doaj +1 more source
Neutrino-Mixing-Generated Lepton Asymmetry and the Primordial $^4$He Abundance [PDF]
, 1999 It has been proposed that an asymmetry in the electron neutrino sector may be generated by resonant active-sterile neutrino transformations during Big Bang Nucleosynthesis (BBN).
B. Acker +24 more
core +2 more sources
Thermodynamic modelling of synthetic communities predicts minimum free energy requirements for sulfate reduction and methanogenesis [PDF]
, 2020 Microbial communities are complex dynamical systems harbouring many species interacting together to implement higher-level functions. Among these higher-level functions, conversion of organic matter into simpler building blocks by microbial communities ...
Chen, Jing +3 more
core +1 more source
Match-communications in Mathematical and in Computer Chemistry, 2023 Machine learning is increasingly popular in predicting chemical reaction performance. This study aims to apply the CatBoost algorithm to build an intelligent prediction system for organic chemical reaction yields.
Hengzhe Wang +6 more
semanticscholar +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Dilepton Production at SPS-energy Heavy Ion Collisions [PDF]
, 1996 The production of dileptons is studied within a hadronic transport model. We investigate the sensitivity of the dilepton spectra to the initial configuration of the hadronic phase in a ultrarelativistic heavy ion collision.
B. Blättel +45 more
core +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Modeling of kerosene combustion under fuel-rich conditions
Advances in Mechanical Engineering, 2017 The turbo-pump and turbine are driven by liquid fuel fed into a gas generator, where the fuel is oxidized with a liquid oxidizing agent. For stable operation of the turbine, the combustion temperature of the gas generator must be maintained below 1000 K.
Eunhye Song, Juhun Song
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source