Results 201 to 210 of about 1,559,834 (252)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Correction: Detection of circovirus and herpesvirus co-infection in suddenly dead common ravens (Corvus corax). [PDF]

Vet Res Commun
Ledwoń A, Sapierzyński R, Dolka B, Witkowska D, Gbylik-Sikorska M, Sell B.   +5 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Towards test guidelines and standards for advanced materials: scientific insights and recommendations from the MACRAMÉ project. [PDF]

Front Toxicol
Pohl A, Haase D, Bleeker EAJ, Ouhajji S, Weltring KM, Wiemann M, Katsumiti A, Seitz C, Gupta G, Ortiz-Galvez LM, Buerki-Thurnherr T, Wick P, Exner TE, Suarez-Merino B, Mentler R, Serchi T, Reilly K, Lynch I, Friedrichs S, Heunisch E.   +19 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Front cover: Historical remarks to the Institute for Chemical Research (ICR)

Front cover: Historical remarks to the Institute for Chemical Research (ICR)
  +6 more sources

Lithium Niobate Electro-Optic Photonic Processor for Variational Quantum Eigensolver. [PDF]

Adv Sci (Weinh)
Lee J, Park UJ, Choi M, Jang HS, Moon S, Hwang H, Seo MK, Ahn DH, Han SW, Kim YS, Kwon H, Jung H.   +11 more
europepmc   +1 more source

RCSB protein data Bank: Next-generation advanced search for exploration of experimental structures and computed structure models. [PDF]

Protein Sci
Rose Y, Brown R, Voigt M, Bhikadiya C, Bittrich S, Duarte JM, Segura J, Green RK, Burley SK.   +8 more
europepmc   +1 more source

Effects of Selenocysteine Substitution on the Cyclotide Kalata B2. [PDF]

Chembiochem
de Boda RLB, Henriques ST, Huang YH, Hernandez CC, Sabido PMG, Craik DJ.   +5 more
europepmc   +1 more source