Results 131 to 140 of about 1,378,218 (287)
Neural stem cell specific fluorescent chemical probe binding to FABP7
, 2012 10.1073/pnas.1200817109Proceedings of the National Academy of Sciences of the United States of America1092610214 ...
Zhai, D. +23 more
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FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Alumni newsletter (University of Illinois at Urbana-Champaign. School of Chemical Sciences)
Vols.
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
INTEGRATION OF ECONOMIC, TECHNICAL AND CHEMICAL SCIENCES FOR SUSTAINABLE DEVELOPMENT
Economics and Environment, 2016 The paper presents the origins of sustainable development, which is considered as an instrument for the greening of the economy. Furthermore, it introduces the discussion about defi ning the term “sustainability” in the economy, including the category ...
Józefa Famielec, Stanisław Famielec
doaj
Research in the chemical sciences: Summaries of FY 1994
, 1994 This summary book is published annually on research supported by DOE`s Division of Chemical Sciences in the Office of Energy Research. Research in photochemical and radiation sciences, chemical physics, atomic physics, chemical energy, separations and ...
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Brain SciencesThe article “Multiple Chemical Sensitivity: A Clinical Perspective”, published in Brain Sciences, suggests that multiple chemical sensitivity (MCS) is primarily a psychogenic disorder, rooted in unresolved emotional trauma and stress responses [...]
Elaine Psaradellis
doaj +1 more source